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TranscriptomicsEthanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression.
Compared gene expression in lymphoblasoid cell lines from alcholics and controls and 24 hr treatment with ethanol. To elucidate the effects of a controlled exposure to ethanol on gene expression, we studied lymphoblastoid cell lines (LCLs) from 21 alcoholics and 21 controls. We cultured each cell li...
ORGANISM(S): Homo sapiens 
2014-10-22 | E-GEOD-52553 | biostudies-arrayexpress
TranscriptomicsKidney Stone Induces Developmental Stage-specific Alterations in Gene Expression
OBJECTIVES: Kidney stone diseases are common in premature infants, but the underlying molecular and cellular mechanisms are not fully defined. We carried out a prospective observational study using microarray analysis to identify factors that may be crucial for the initiation and progression of ston...
ORGANISM(S): Mus musculus 
2010-01-13 | E-GEOD-18160 | biostudies-arrayexpress
TranscriptomicsMethylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines
DNA from Epstein-Barr virus (EBV)-transformed lymphocyte cell lines (LCLs) has proven very useful for studies of genetic sequence polymorphisms. Whether EBV-LCL DNA is suitable for methylation studies is less clear. We conduct a genome-wide methylation investigation using an array set with 45 millio...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-35204 | biostudies-arrayexpress
GenomicsCIDR: Collaborative Study on the Genetics of Alcoholism Case Control Study

This is a case-control study of alcoholism, in which the subjects have been drawn from the Collaborative Study on the Genetics of Alcoholism (COGA), a large, ongoing family-based study that includes subjects from seven sites around the US. COGA has gathered detailed, standardized data on ...

phs000125.v1.p1 | EGA
GenomicsStudy of Addiction: Genetics and Environment (SAGE)

This study is part of the Gene Environment Association Studies initiative (GENEVA) funded by the National Human Genome Research Institute. The overarching goal is to identify novel genetic factors that contribute to addiction through a large-scale genome-wide association study of DSM-IV alcoh...

phs000092.v1.p1 | EGA
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