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MetabolomicsSterol-O acyltransferase inhibition ameliorates high-fat diet-induced renal fibrosis and tertiary lymphoid tissue maturation after ischemic reperfusion injury (Mice+diet analysis)

Metabolic syndrome is a growing global health problem and is strongly associated with the development of chronic kidney disease (CKD). Recently, the prevalence of CKD has been increasing worldwide, particularly among the older adults. We previously demonstrated that aged kidneys are prone to deve...

2022-12-05 | MTBLS4994 | MetaboLights
MetabolomicsSterol-O acyltransferase inhibition ameliorates high-fat diet-induced renal fibrosis and tertiary lymphoid tissue maturation after ischemic reperfusion injury (Mice+injury analysis)

Metabolic syndrome is a growing global health problem and is strongly associated with the development of chronic kidney disease (CKD). Recently, the prevalence of CKD has been increasing worldwide, particularly among the older adults. We previously demonstrated that aged kidneys are prone to deve...

2022-12-05 | MTBLS4988 | MetaboLights
ProteomicsOne-dimensional capillary liquid chromatographic separation coupled with tandem mass spectrometry unveils the Escherichia coli proteome on a microarray scale.
We successfully identified the proteome expressed in Escherichia coli (E. coli) cells on a microarray scale using one-dimensional capillary liquid chromatography-tandem mass spectrometry (LC-MS/MS) with a 350 cm long, 100 microm i. d., monolithic silica-C(18) capillary column. E. coli tryptic digest...
ORGANISM(S): Escherichia Coli 
2016-07-20 | PXD004605 | JPOST Repository
TranscriptomicsFKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance.
Glucocorticoid excess is linked to central obesity, adipose tissue insulin resistance and type 2 diabetes mellitus. The aim of our study was to investigate the effects of dexamethasone on gene expression in human subcutaneous and omental adipose tissue, in order to identify potential novel mechanism...
ORGANISM(S): Homo sapiens 
2014-08-18 | E-GEOD-42902 | biostudies-arrayexpress
TranscriptomicsGene expression in normal tissues detected by newly developed chicken 44K microarray
Chicken 60-mer oligonucleotide microarray, including 39854 cDNA and ESTs, entire Marek’s disease virus and avian influenza virus genomes, and 150 chicken microRNAs, was developed. Cecal tonsil, ileum, liver and spleen from 6 chickens were selected for hybridization to validate the microarray perform...
ORGANISM(S): Gallus gallus 
2008-02-28 | E-GEOD-7452 | biostudies-arrayexpress
TranscriptomicsDevelopment and validation of a 31,918-genes oyster cDNA Microarray: Tissue-specific expression profiles
Research using the oyster Crassostrea gigas as a model has experienced a rapid growth in recent years thanks to the development of high throughput molecular technologies. As many as 56,268 EST sequences have so far been sequenced, representing a genome-wide resource that can be used for microarray i...
ORGANISM(S): Crassostrea gigas 
2011-10-15 | E-GEOD-26265 | biostudies-arrayexpress
TranscriptomicsThe Applied Biosystems Tissue Gene Expression Database - Human Body Map. A whole genome survey of 32 Human Tissues
The Applied Biosystems Tissue Gene Expression Database, known as the Human Body Map, is a collection of gene expression profiles from 31 normal tissues and a Universal Human Reference RNA (Stratagene). The Human BodyMap was created using the Applied Biosystems Expression Array System. There were thr...
ORGANISM(S): Homo sapiens 
2007-06-04 | E-GEOD-7905 | biostudies-arrayexpress
OtherDiscovery of colorectal cancer biomarker candidates by membrane proteomic analysisand subsequent verification using selected reaction monitoring and tissue microarrayanalysis
Data from ProteomeXchange, PXD ID: PXD000851. File: iTRAQ3.msf.mgf. Published as part of Mol Cell Proteomics. 2014 Mar 31 . From the Abstract: {{i}} We here performed a quantitative proteomic analysis of membrane fractions from colorectal cancer tissue to discover biomarker candidates, and then ext...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210027051 | GPMDB
Resource Reanalysis 
TranscriptomicsA saturated fatty acid rich diet can induce an 'obese-like' gene expression profile in adipose tissue
We investigated the effect of a saturated (SFA) and a monounsaturated (MUFA) rich diet on insulin sensitivity and adipose tissue gene expression profiles of subjects at risk for metabolic syndrome. A controlled-feeding trial was performed with 20 moderately overweight subjects. Subjects received a S...
ORGANISM(S): Homo sapiens 
2010-02-13 | E-GEOD-14954 | biostudies-arrayexpress
TranscriptomicsComparison of steady state mRNA levels between equine articular cartilage and ten other equine tissues
A tissue survey of gene expression was conducted using microarray-based transcriptional profiling to compare equine articular cartilage to 10 other normal adult horse tissues. The ten comparative tissues were bladder, cerebellum, kidney, liver, lung, lymph node, muscle, placental villous, spleen, a...
ORGANISM(S): Equus caballus 
2011-01-27 | E-GEOD-23862 | biostudies-arrayexpress
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