Tiwari Vijay K VK

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Sox4 is a master regulator of epithelial-mesenchymal transition (EMT) by controlling Ezh2 expression and epigenetic reprogramming

Gene expression profiling has uncovered the transcription factor Sox4 with up-regulated activity during TGFÎ²-induced EMT in normal and cancerous breast epithelial cells. Sox4 is indispensable for EMT and cell survival in vitro and for primary tumor growth and metastasis in vivo. Among several EMT-r...

ORGANISM(S): Mus musculus

2013-06-20 | E-GEOD-45579 | biostudies-arrayexpress

Expression data from Top2β KO cells as well ICRF-193 treatment of in vitro derived neurons and cortical glutamatergic neurons

Expression profiling of from Top2β knokout and ICRF-193 treated neurons reveals a significant number of genes that are transcriptionally deregulated Gene expression in the Top2β knocnout ES, NP and TN stages of stem cell differention to the corresponidng wild type cells. In vitro derived neurons and...

ORGANISM(S): Mus musculus

2012-05-01 | E-GEOD-27245 | biostudies-arrayexpress

NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program

Cell fate specification relies on the action of critical transcription factors that become available at distinct stages of embryonic development. One such factor is NeuroD1, which is essential for eliciting the neuronal development program and possesses the ability to reprogram other cell types into...

ORGANISM(S): Mus musculus

2015-11-02 | E-GEOD-65072 | biostudies-arrayexpress

Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells (ChIP-chip)

Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a unipotent fate. This process was suggested to coincide with a global increase of repressive heterochromatin, which results in a reduction of transcriptional plasticity and potential. Here we report the dynami...

ORGANISM(S): Mus musculus

2011-06-21 | E-GEOD-27724 | biostudies-arrayexpress

Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells (RNA-seq)

ORGANISM(S): Mus musculus

2011-06-21 | E-GEOD-27843 | biostudies-arrayexpress

A chromatin-modifying function of JNK during stem cell differentiation

Signaling mediates cellular responses to extracellular stimuli. The c-Jun NH2-terminal kinase (JNK) pathway exemplifies one sub-group of Mitogen-activated protein (MAP) kinases, which besides established functions in stress response, also contributes to developmental processes by an unknown mechanis...

ORGANISM(S): Mus musculus

2011-12-18 | E-GEOD-25532 | biostudies-arrayexpress

Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells (ChIP-seq)

ORGANISM(S): Mus musculus

2011-06-21 | E-GEOD-27827 | biostudies-arrayexpress

Research priorities in Maternal, Newborn, & Child Health & Nutrition for India: An Indian Council of Medical Research-INCLEN Initiative.

Not available

S-EPMC5644295 | biostudies-literature

Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study.

Not available

S-EPMC8634634 | biostudies-literature

A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.