Sort   by:  
 Page size 
TranscriptomicsMicroarray analysis of gene expression profiles in response to tomato leaves extract treatment in MCF-7 breast cancer cells
Microarray analysis was performed to evaluate the global gene expression profiles of MCF-7 breast cancer cells treated with tomato leaves extract (TLE) in 1 hr and 48 hrs of treatment. Several of genes with p < 0.05 and fold-change cut-off <2.00 from human genome had significantly changed after the ...
ORGANISM(S): Homo sapiens 
2011-11-05 | E-GEOD-33443 | biostudies-arrayexpress
no omics definedTranscription profiling of human hippocampi from epilepsy patients with and without hippocampal sclerosis and autopsy controls
Genome wide gene expression was compared between nonHS, HS temporal lobe epilepsy patients (TLE) and autopsy control hippocampi in a 3-way analysis. In many TLE patients the hippocampus is subject to massive neuronal damage, gliosis and hippocampal sclerosis (HS), while in others there is no apparen...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-MEXP-744 | biostudies-arrayexpress
GenomicsAgo iCLIP of TLE patient resected hippocampus
Ago iCLIP of TLE patient resected hippocampus
PRJNA884734 | ENA
TranscriptomicsCuproptosis-related genes signature and validation of differential expression and the potential targeting drugs in temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is the most common subtype of epilepsy in adults and is characterized by neuronal loss, gliosis, and sprouting mossy fibers in the hippocampus. But the mechanism underlying neuronal loss has not been fully elucidated. A new programmed cell death, cuproptosis, has recentl...
ORGANISM(S): Homo sapiens 
2023-06-20 | E-MTAB-13092 | biostudies-arrayexpress
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
GenomicsThe Tbx20-TLE Interaction is Essential for the Maintenance of the Second Heart Field
The Tbx20-TLE Interaction is Essential for the Maintenance of the Second Heart Field
PRJNA1009104 | ENA
UnknownTranscription factors FOXG1 and Groucho/TLE promote glioblastoma growth.
Not available
S-EPMC3984242 | biostudies-literature
GenomicsAgo iCLIP of TLE patient resected hippocampus
Nine patients with temporal lobe epilepsy (TLE) underwent hippocampal resection. Six had hippocampal sclerosis, three did not show signs of hippocampal sclerosis. Resected hippocampi were used for Ago iCLIP to detect miRNA targeting in the resected tissue.
ORGANISM(S): Homo sapiens 
2023-06-02 | GSE214317 | GEO
UnknownVolumetric and structural connectivity abnormalities co-localise in TLE.
Not available
S-EPMC9421455 | biostudies-literature
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
Sort   by:  
 Page size