Sort   by:  
 Page size 
Background Complex diseases are often difficult to diagnose, treat and study due to the multi-factorial nature of the underlying etiology. Large data sets are now widely available that can be used to define novel, mechanistically distinct disease subtypes (endotypes) in a completely data-driven mann...
ORGANISM(S): Homo sapiens 
Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics. Here we analyse systematically more than 70 pairs of primary human colon tumours by applying next-generation sequencing to characterize their exomes, transcriptomes and copy-number alte...
Data Access Committee EGAC00001000055
Wilson and King were among the first to recognize that the extent of phenotypic change between humans and great apes was dissonant with the rate of molecular change. Proteins are virtually identical; cytogenetically there are few rearrangements that distinguish ape-human chromosomes; rates of single...
ORGANISM(S): Pan troglodytes 
Colon matched tumour samples
Colon tumour samples
Exome capture sequencing of colon tumor/normal pairs
RNA sequencing of colon tumor/normal sample pairs
Whole genome sequencing of colon samples
Sort   by:  
 Page size