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MetabolomicsHuman Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including social communication and stereotypies. In addition to genetic risks, the gut microbiome differs between typically-developing (TD) and ASD individuals, though it remains unclear whether the microbiome contrib...
2019-07-04 | MTBLS726 | MetaboLights
MetabolomicsPeripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models
Reversible and sub-lethal stresses to the mitochondria elicit a program of compensatory responses that ultimately improve mitochondrial function, a conserved anti-aging mechanism termed mitohormesis. Here, we show that harmol, a member of the beta-carbolines family with anti-depressant properties, i...
2023-05-26 | MTBLS7533 | MetaboLights
TranscriptomicsTranscription profiling of human colorectal carcinoma-derived cell lines, p53 -/-, +/-, +/+ at 0 and 12 hrs after growth arrest
Human colorectal carcinoma-derived cell lines, p53 -/-, +/-, +/+ at 0 and 12 hrs after growth arrest.
ORGANISM(S): Homo sapiens 
2007-09-28 | E-GEOD-90 | biostudies-arrayexpress
UnknownInsulin sensitivity and complications in type 1 diabetes: New insights.
Not available
S-EPMC4317319 | biostudies-literature
Unknown3D Network exploration and visualisation for lifespan data.
Not available
S-EPMC6199797 | biostudies-literature
TranscriptomicsRepression of meiotic genes by antisense transcription and by Fkh2 transcription factor in Schizosaccharomyces pombe
In S. pombe, about 5% of genes are meiosis-specific and accumulate little or no mRNA during vegetative growth. Here we use Affymetrix tiling arrays to characterize transcripts in vegetative and meiotic cells. In vegetative cells, many meiotic genes, especially those induced in mid-meiosis, have ab...
ORGANISM(S): Schizosaccharomyces pombe 
2011-11-01 | E-MEXP-3414 | biostudies-arrayexpress
UnknownCollege Students' Reasons for Leaving Biomedical Fields: Disenchantment with Biomedicine or Attraction to Other Fields?
Not available
S-EPMC7989803 | biostudies-literature
UnknownA metabolic perspective of selection for fruit quality related to apple domestication and improvement.
Not available
S-EPMC10131461 | biostudies-literature
TranscriptomicsTranscription profiling by array of Arabidopsis mutant for rhd2/ArtbohC
Aim: To determine the effect of an AtrbohC mutation on the gene expression pattern in primary root tissue, to identify candidate genes acting downstream of AtrbohC, particularly any encoding antioxidant-related proteins, signal transduction components or proteins known to be required for normal roo...
ORGANISM(S): Arabidopsis thaliana 
2008-06-14 | E-GEOD-6165 | biostudies-arrayexpress
TranscriptomicsBMP and Activin treatment of mouse extraembryonic endoderm (XEN) cells
XEN cells are derived from the primitive endoderm of mouse blastocysts. In culture and in chimeras they exhibit properties of parietal endoderm. However, BMP signaling promotes XEN cells to form an epithelium and differentiate into visceral endoderm (VE). Of the several different subtypes of VE desc...
ORGANISM(S): Mus musculus 
2011-11-10 | E-GEOD-32199 | biostudies-arrayexpress
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