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Transcriptomics5'-RNAseq of 5'-enriched primary coding RNA in Staphylococcus aureus wildtype under 30 min allicin stress to detect Transcription Start Sites
To detect Transcription Start sites (TSS) in Staphylococcus aureus a cDNA library enriched for primary 5′-transcripts according to Peifer-Sancar et al. (2013) was prepared and sequenced on Illumina MiSeq system to retrieve 5′-ends of primary transcripts. Cultivation was performed in Luria Bertani (L...
ORGANISM(S): Staphylococcus aureus 
2021-10-25 | E-MTAB-10889 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of human bronchoalveolar lavage and lung biopsy samples in the segmental endotoxin challenge model
Segmental instillation of lipopolysaccharide (LPS) by bronchoscopy can be used as a model to safely induce transient airway inflammation in the human lung. The LPS challenge model enables investigation of cellular mechanisms involved in pulmonary inflammatory processes as well as pharmacodynamic ana...
ORGANISM(S): Homo sapiens 
2024-03-01 | E-MTAB-13318 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of wild type pea seeds and seeds with embryo-specific expression of a bacterial trehalose 6-phosphate phosphatase (TPP), encoded by the otsB gene to investigate the influence of decreased T6P content on gene expression in developing cotyledons.
MAGE-TAB Version
ORGANISM(S): Pisum sativum 
2018-06-01 | E-MTAB-6659 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae
In this study we focus on two Saccharomyces cerevisiae strains with varying production of heterologous M-NM-1-amylase and we compare the metabolic fluxes and transcriptional regulation at aerobic and anaerobic conditions, in particular with the objective to identify the final electron acceptor for p...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-17 | E-GEOD-38848 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonic kidney cell line HEK293T to investigate the effects of overexpression of FoxO4 or mutated FoxO4 in presence or absence of p300
Effects of overexpression of FoxO4 or mutated FoxO4 in presence or absence of p300 overexpression
ORGANISM(S): Homo sapiens 
2009-07-30 | E-MTAB-4 | biostudies-arrayexpress
TranscriptomicsCP003: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35703 | biostudies-arrayexpress
TranscriptomicsCP001: Modulation of glutamine metabolism by the PI3K-PKB/c-akt-FOXO network regulates autophagy
The PI3K-PKB/c-akt-FOXO signalling network provides a major intracellular hub for regulation of cell proliferation, survival and stress resistance1. Here we report a novel function for FOXO transcription factors in regulating autophagy through modulation of intracellular glutamine levels. To identif...
ORGANISM(S): Mus musculus 
2012-07-21 | E-GEOD-35701 | biostudies-arrayexpress
Genomicsena-DATASET-LUMC-SASC-04-12-2017-12:12:33:008-298 - samples
Patient information SSc patients were recruited at the Department of Rheumatology of the Leiden University Medical Center (Leiden, The Netherlands). All patients met the American Rheumatism Association classification criteria for SSc (Subcommittee for scleroderma criteria 1980), and were classified ...
EGAD00001003832 | EGA
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