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TranscriptomicsGenetically-driven target tissue over-expression of CD40: A novel mechanism in autoimmune disease
The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid derived cells, many of which are targets for tissue specific autoimmune diseases, including d thyroid follicular cells in Graves’ disease (GD). Whether target tissue CD40 expression plays a role in au...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-39081 | biostudies-arrayexpress
ProteomicsThe ribotoxic stress response drives UV-mediated cell death.
Supporting raw MS data for paper (doi: 10.1016/j.cell.2024.05.018) by Sinha N.K. et al, titled "The ribotoxic stress response drives UV-mediated cell death". Index of MS files and labels Table S1 - HaCaT Timecourse. 1-1 - Proteome (AO3604-3627 | Unimod:35; 2016; 4 | 126 -UT_01; 127n - UT_02; 12...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-07-25 | MSV000092521 | MassIVE
ProteomicsMotif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity
Plant cell surface pattern recognition receptors (PRRs) perceive non- or altered-self elicitors to induce immune responses. PRRs relay information across the plasma membrane and trigger downstream signaling via receptor-like cytoplasmic kinases (RLCKs) such as BOTRYTIS-INDUCED KINASE 1 (BIK1). BIK1 ...
ORGANISM(S): Arabidopsis Thaliana 
PXD066643 | panorama
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