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TranscriptomicsExpression data of cystic renal epithelial tissue from mice deficient for fumarate hydratase.
Fumarate hydratase (FH) mutations cause hereditary leiomyomatosis and renal cell cancer (HLRCC). We have conditionally inactivated the murine ortholog (Fh1) in renal tubular epithelial cells in order to generate an in vivo model of HLRCC. Fh1 knockout mice recapitulates important aspects of HLRCC in...
ORGANISM(S): Mus musculus 
2010-12-22 | E-GEOD-10989 | biostudies-arrayexpress
GenomicsChIP Seq of Oct4, Nanog, H3K27me3 in Oct4+/+ and Oct4 +/- mES cells
Embryonic stem cell (ESC) pluripotency is governed by a gene regulatory network centred on the transcription factors Oct4 and Nanog. ESCs fluctuate between states of high and low Nanog expression that direct efficient or inefficient self-renewal. To date, robust self-renewing ESC states have only be...
ORGANISM(S): Mus musculus 
2013-05-07 | E-MTAB-1617 | biostudies-arrayexpress
UnknownGenetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.
Not available
S-EPMC4879695 | biostudies-literature
Genomicsena-DATASET-ICR-PTGT-15-10-2018-17:54:40:362-3 - samples
BAM files of individuals from the 1958BC aligned to hg17
EGAD00001004396 | EGA
GenomicsICR MOPOPGEN UK exome control series
ICR MOPOPGEN UK exome control series
EGAS00001001667 | EGA
TranscriptomicsTranscription profiling of human primary colorectal cancers
Samples were taken from colorectal cancers in surgically resected specimens from 74 patients. The expression profiles were determined using Affymetrix Human Genome U133Plus 2.0 arrays. Our MSI/MSS classifer was applied to these samples. Experiment Overall Design: mRNA from 74 fresh-frozen primary co...
ORGANISM(S): Homo sapiens 
2009-01-16 | E-GEOD-13067 | biostudies-arrayexpress
UnknownAge- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.
Not available
S-EPMC5019754 | biostudies-literature
Genomicsena-DATASET-WIMM-10-10-2016-16:24:16:111-38 - samples
Whole Genome Sequencing data set for the study "Premalignant SOX2 in ovarian cancer patients"
EGAD00001002734 | EGA
GenomicsPremalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies
To identify early driver mutations in ovarian cancer cells, we used dense whole genome sequencing of micrometastases and microscopic residual disease collected at three time points from a single patient during treatment for high-grade serous ovarian cancer (HGSOC). Laser capture microdissection of t...
EGAS00001001909 | EGA
GenomicsOvarian Cancer Laboratory, University of Oxford
Data Access Committee EGAC00001000518
EGAC00001000518 | EGA
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