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This repository contains all the FASTQ files for the five data modalities (scRNA-seq, scATAC-seq, Multiome, CITE-seq+scVDJ-seq, and spatial transcriptomics) used in the article \\"An Atlas of Cells in The Human Tonsil,\\" published in Immunity in 2024. Inspired by the TCGA barcodes, we have named ea...
ORGANISM(S): Homo sapiens 
Single cell RNA-sequencing of human tonsil Innate lymphoid cells (ILCs) from three independent tonsil donors. Sequencing libraries were prepared from FACS sorted individual ILCs with the Smart-Seq2 protocol (Picelli et al. Nature Methods 2013)
ORGANISM(S): Homo sapiens 
Deciphering the intricate tumor-immune interactions within the microenvironment is crucial for advancing cancer immunotherapy. Here, we introduced mipDVP, an advanced approach integrating highly multiplexed imaging, single-cell laser microdissection, and sensitive mass spectrometry to spatially prof...
ORGANISM(S): Homo sapiens (Human) 
2024-12-19 | PXD057118 | Pride
In vivo antigen (Ag)-induced differentiation of B lymphocytes into plasma cells (PCs) takes place in extra-follicular foci and germinal centers of the secondary lymphoid organs (SLOs). Most of these SLO PCs are short-living and only relatively few PCs, characterized by secreting high-affinity antibo...
ORGANISM(S): Homo sapiens 
Tonsil cancer compared with normal tonsil tissue
Human tonsil tissue sequencing datasets, which include spatial antigen receptor repertoire profiling and spatial transcriptomics (Visium). This study includes two samples.
This SuperSeries is composed of the following subset Series: GSE13397: HNSCC samples vs. normal tonsil samples: self-self hybridization design GSE13398: HNSCC samples vs. normal tonsil samples: reference design Refer to individual Series
ORGANISM(S): Homo sapiens 
To study characteristics of the orapharyngeal epithelia which may influence susceptibility or resistance to HIV, we performed microarray analysis of the tonsil and gingival epithelium.Tonsil epithelium has been implicated in HIV pathogenesis, but its role in oral transmission remains controversial. ...
ORGANISM(S): Homo sapiens 
transcription profiling of human head and neck squamous cell carcinoma (HNSCC) samples vs. normal tonsil samples using a self-self hybridization experimental design on two-color arrays. Used to identify differentially expressed genes in tumor/normal samples, and compare the result to that of the sam...
ORGANISM(S): Homo sapiens 
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