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TranscriptomicsTranscription profiling of rat uterus after exposure to 17 alpha-ethynyl estradiol for different lengths of time
The rat uterus responds to acute estrogen treatment with a series of well characterized physiological responses; however, the gene expression changes required to elicit these responses have not been fully characterized. In order to understand early events induced by estrogen exposure in vivo, we ev...
ORGANISM(S): Rattus norvegicus 
2007-04-05 | E-MEXP-999 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of zebrafish livers following exposure to 17 alpha-ethynylestradiol (EE2) at 0, 15, 40, or 100 ng/L
Genomic, proteomic, and metabolomic technologies continue to receive increasing interest from environmental toxicologists. This interest is due to the great potential of these technologies to identify detailed modes of action and to provide assistance in the evaluation of a contaminant?s risk to aq...
ORGANISM(S): Danio rerio 
2007-02-24 | E-TABM-105 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testis by transplacental exposure to estrogen receptor (ER) agonists - high and low doses of 17a-Ethynyl estradiol, genistein or bisphenol A
The purpose of this study was to determine 1) the transcriptional program elicited by exposure to three estrogen receptor (ER) agonists: 17 a-ethynyl estradiol (EE), genistein (Ges) and bisphenol A (BPA) during fetal development of the rat testis and epididymis; and 2) whether very low dosages of es...
ORGANISM(S): Rattus norvegicus 
2005-05-18 | E-TABM-12 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of immature rat uterus ovaries in response to 17-alpha-ethynyl estradiol
BACKGROUND: In a previous study, we determined the effects of 17-alpha-ethynyl estradiol (EE) [CAS:57-63-6;CHEBI:4903] on gene expression using microarrays that represented approximately 9,000 genes, which was the state of-the-art. Higher content arrays with almost double the number of genes have si...
ORGANISM(S): Rattus norvegicus 
2006-11-14 | E-TOXM-20 | biostudies-arrayexpress
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