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TranscriptomicsDistinct processes and transcriptional targets underlie CDX2 requirements in intestinal stem cells and differentiated villus cells
To define target genes of the intestine-restricted transcription factor (TF) CDX2 in intestinal stem cells, we performed chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-Seq). We used RNA-sequencing to profile gene expression changes during cell differentiation from mouse ...
ORGANISM(S): Mus musculus 
2015-09-15 | E-GEOD-70766 | biostudies-arrayexpress
TranscriptomicsEngineered stomach tissue as a renewable source of functional beta-cells for blood glucose regulation
The gastrointestinal (GI) epithelium is a highly regenerative tissue with the potential to provide a renewable source of insulin+ cells using cellular reprogramming. Here, we describe the antral stomach as a previously unrecognized source highly amenable to conversion into functional insulin-secret...
ORGANISM(S): Mus musculus 
2016-01-09 | E-GEOD-76686 | biostudies-arrayexpress
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