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Myeloid cell lines (K562 and HEL) were treated overnight with CHIR99021 or a vehicle control (DMSO). CHIR99021 treatment inhibits GSK3B within the destruction complex functioning in Wnt/beta-catenin signalling pathway, thereby preventing beta-catenin degradation and promoting its stabilization. Foll...
ORGANISM(S): Homo sapiens 
RNA extracted from Drosophila wandering L3 wing imaginal discs was 2S rRNA depleted and prepared for miRNA sequencing using the QIAseq miRNA Library kit. The experiment was performed on Pacman and Dis3L2 null mutants and their respective isogenic control lines with four replicates of each condition.
ORGANISM(S): Drosophila melanogaster 
RNA-seq of ribosome depleted RNA extracted from SAOS-2 cells following treatment with either XRN1 siRNA or a scrambled siRNA control
ORGANISM(S): Homo sapiens 
RNA extracted from whole blood of healthy controls or podoconiosis patients and subject to RNA sequencing. Total RNA libraries were prepared using the QIAseq Stranded RNA library kit with rRNA and globin RNA depleted using the QIAseq FastSelect rRNA and globin mRNA removal kit.
ORGANISM(S): Homo sapiens 
We investigated the effect on miRNA expression in Drosophila melanogaster wing imaginal discs following the knockdown of the 3'-5' exoribonuclease Dis3.
ORGANISM(S): Drosophila melanogaster 
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