Townley S L SL - OmicsDI

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We have completed the high quality reference genome for domestic sheep (Oar v3.1). Early-stage Illumina GA sequence platform sequenced less reads in high GC content regions than in other regions. To read through higher GC content regions, we generated 2 Gb MeDIP-seq data for filling gaps in sheep re...

ORGANISM(S): Ovis aries

2014-06-06 | E-GEOD-56644 | biostudies-arrayexpress

PHD2/3-dependent hydroxylation of thyroid hormone receptor-Î± mediates the transcriptional regulation of phospholamban to tune the cardiac response to chronic Î²-adrenergic stress

Ischemic heart disease is the leading cause of heart failure. Both clinical trials and experimental animal studies demonstrate that chronic hypoxia can induce contractile dysfunction even before substantial ventricular damage, implicating a direct role of oxygen in the regulation of cardiac contract...

ORGANISM(S): Mus musculus

2016-04-01 | E-GEOD-67726 | biostudies-arrayexpress

Circulating microRNAs predict biochemical recurrence in prostate cancer patients

Comparison of circulating miRNA levels in patients who experienced rapid biochemical recurrence or no recurrence following radical prostatectomy qRT-PCR miRNA expression profiling of patient serum

ORGANISM(S): Homo sapiens

2013-05-22 | E-GEOD-47125 | biostudies-arrayexpress

Participant acceptability and clinician satisfaction of cognitive behavioural therapy and medication management algorithm compared with enhanced standard care for treatment of depression among youth with HIV.

Not available

S-EPMC12439113 | biostudies-literature

Pharmacokinetics, safety, and tolerability of dispersible and immediate-release abacavir, dolutegravir, and lamivudine tablets in children with HIV (IMPAACT 2019): week 24 results of an open-label, multicentre, phase 1-2 dose-confirmation study.

Not available

S-EPMC10642428 | biostudies-literature

Safety of combined long-acting injectable cabotegravir and long-acting injectable rilpivirine in virologically suppressed adolescents with HIV (IMPAACT 2017/MOCHA): a phase 1/2, multicentre, open-label, non-comparative, dose-finding study.

Not available

S-EPMC12087306 | biostudies-literature

Safety and immunogenicity of concomitant administration of COVID-19 vaccines (ChAdOx1 or BNT162b2) with seasonal influenza vaccines in adults in the UK (ComFluCOV): a multicentre, randomised, controlled, phase 4 trial.