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TranscriptomicsColon biopsies from Crohns patients and healthy controls
The aim of this study was to investigate differential intestinal gene expression in patients with Crohn's disease (CD) and controls. 172 biopsies from CD and control subjects were studied. Endoscopic biopsies were taken at ileocolonoscopy from five specific anatomical locations including the termi...
ORGANISM(S): Homo sapiens 
2010-07-19 | E-GEOD-20881 | biostudies-arrayexpress
TranscriptomicsColon biopsies from UC patients and healthy controls
Transcriptional profiling of colon epithelial biopsies from ulcerative colitis patients and healthy control donors. Study aims to survey and analyze variation from disease in different GI regions. Keywords: disease state analysis Biopsies from a variety of anatomic locations, from patients of variou...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-11223 | biostudies-arrayexpress
ProteomicsEnhancing the bothropic antivenom through a reverse antivenomics approach
Antivenoms are the only effective treatment for snakebite envenomation and have saved countless lives over more than a century. Despite its value, antivenoms often present risks of adverse reactions. Current formulations contain a substantial fraction of non-specific antibodies and serum proteins th...
ORGANISM(S): Equus Caballus (ncbitaxon:9796) 
2024-11-07 | MSV000096324 | MassIVE
TranscriptomicsMolecular Classification of AIDS-Related Lymphomas [including third-party data]
Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphom...
ORGANISM(S): Homo sapiens 
2012-07-17 | E-GEOD-17372 | biostudies-arrayexpress
TranscriptomicsMolecular Classification of AIDS-Related Lymphomas
Gene expression profiling (GEP) of ARL patient samples was done to determine whether gene expression signatures derived from HIV- lymphomas retained their ability to molecularly classify HIV+ lymphomas. The GEP-based predictors robustly classified ARL tumors, distinguishing molecular Burkitt lymphom...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-GEOD-17189 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of genes impacted by 5 day knockdown of SLC24A5 in normal human melanocytes.
A major development in pigmentation research was the discovery of the involvement of SLC24A5 in natural variation in skin colour. This study used Agilent whole-genome microarrays to examine the impact of SLC24A5 knockdown on the transcriptome of normal human melanocytes derived from lightly and dark...
ORGANISM(S): Homo sapiens 
2012-04-25 | E-GEOD-21565 | biostudies-arrayexpress
TranscriptomicsThrombopoietin (TPO) protects against heart damage induced by doxorubicin and infarction in rat models
In order to examine the mechanism of TPO on cardiac protection against DOX damage, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to delineate the TPO cardioprotective mechanism against DOX-induced cardiomyopathy Dox and TPO...
ORGANISM(S): Rattus norvegicus 
2010-12-29 | E-GEOD-15449 | biostudies-arrayexpress
Genomicsena-DATASET-Genentech-07-10-2014-17:32:07:354-3 - samples
nccRCC Whole Exome sequencing data (consented samples only)
EGAD00001001023 | EGA
GenomicsnccRCC_Illumina_2.5M - samples
nccRCC tumor/normal genotypes
EGAD00010000648 | EGA
Genomicsena-DATASET-Genentech-07-10-2014-17:28:50:781-2 - samples
nccRCC RNA-Seq data of consented samples
EGAD00001001022 | EGA
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