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TranscriptomicsExpression data from ileum of mice suffered from subchronic and mild social defeat stress
This study aimed to investigate the effects of depression on transcriptome in ileum using a subchronic and mild social defeat stress (sCSDS) model. In addition to exhibiting social deficit and hyperphagia-like behavior, the sCSDS mice keep much more water in their body than control mice. In order to...
ORGANISM(S): Mus musculus 
2016-08-03 | E-GEOD-64004 | biostudies-arrayexpress
TranscriptomicsCritical role of SOX17 in the hematopoietic development from human embryonic stem cells
Human embryonic stem cells (hESCs) are a powerful tool for modeling regenerative therapy. To search for the genes that promote hematopoietic development from human pluripotent stem cell, we overexpressed a list of hematopoietic regulator genes in human pluripotent stem cell-derived CD34+CD43- endoth...
ORGANISM(S): Homo sapiens 
2012-12-14 | E-GEOD-38156 | biostudies-arrayexpress
TranscriptomicsChIP-on-chip data from human ES cells-derived CD34+CD43+CD45low cells (hemogenic endothelium-like cells) overexpressing 3xFLAG-Sox17-ERT
Overexpression of transcription factor Sox17 in human ES cells-derived endothelial cells enhances expansion of hemogenic endothelium-like cells. Human ES cells were differentiated for 6 days in EBs, then CD34+CD43-CD45- endothelial cells were isolated, plated onto OP9 cells, and transduced with the ...
ORGANISM(S): Homo sapiens 
2012-12-14 | E-GEOD-37528 | biostudies-arrayexpress
TranscriptomicsHoxB4 in hematopoietic stem cells
Ectopic expression of homeodomain transcription factor HoxB4 in mouse ES cells enhances in vitro development of hematopoietic stem cells (HSCs). Mouse ES cells were differentiated for 6 days in EBs, then c-Kit+CD41+ hematopoietic precursor cells were isolated, plated onto OP9 cells, and transduced w...
ORGANISM(S): Mus musculus 
2011-05-23 | E-GEOD-26653 | biostudies-arrayexpress
TranscriptomicsExpression data of human ES cells-derived CD34+CD43+CD45low cells (hemogenic endothelium-like cells) expanded upon overexpression of Sox17
Overexpression of transcription factor Sox17 in human ES cells-derived endothelial cells and hematopoietic cells enhances expansion of hemogenic endothelium-like cells. Human ES cells were differentiated for 6 days, 8 days or 12 days in EBs, then CD34+CD43-CD45- endothelial cells, CD34+CD43+CD45- pr...
ORGANISM(S): Homo sapiens 
2012-12-14 | E-GEOD-37348 | biostudies-arrayexpress
TranscriptomicsDevelopmental gene expression of Xenopus laevis J strain [stage]
Comprehensive RNA-seq experiments to measure the expression of homoeologs across different developmental stages, as a part of the Xenopus laevis genome project. This work is funded by Agency Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT; "Genome Science" Gra...
ORGANISM(S): Xenopus laevis 
2016-10-24 | E-GEOD-73430 | biostudies-arrayexpress
TranscriptomicsTissue gene expression of Xenopus laevis J strain [tissue]
Comprehensive RNA-seq experiments to measure the expression of homoeologs across different tissues, as a part of the Xenopus laevis genome project. This work is funded by Agency Japanese Ministry of Education, Culture, Sports, Science and Technology (MEXT; "Genome Science" Grant ID 221S000...
ORGANISM(S): Xenopus laevis 
2016-10-24 | E-GEOD-73419 | biostudies-arrayexpress
TranscriptomicsAnalysis of small RNAs in piRNA pathway mutant mouse testes
Piwi-interacting RNAs are 25-32 nt small RNAs bound to Piwi proteins. To know the steps where factors involved in the piRNA biogenesis (MILI, MIWI2, ZUC (MitoPLD), MVH) work, we sequenced small RNAs from mutant mouse testes and analyzed piRNAs. Examination of small RNAs in testes of mutant mouse
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-20327 | biostudies-arrayexpress
UnknownArms race between anti-silencing and RdDM in noncoding regions of transposable elements
Not available
S-SCDT-10_15252-EMBR_202256678 | biostudies-other
TranscriptomicsMicroRNA expression profiling predicts clinical outcome of chronic hepatitis C by interferon administration
We attempt to catalog the microRNA (miRNA) expression profile according to the response of combination therapy in order to predict the outcome of drug-response before administration and clarify the relationship between aberrant expression of miRNAs and chronic liver disease. We quantified expression...
ORGANISM(S): Homo sapiens 
2010-12-30 | E-GEOD-16922 | biostudies-arrayexpress
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