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UnknownN-Terminal pro-Brain Natriuretic Peptide and Associations With Brain Magnetic Resonance Imaging (MRI) Features in Middle Age: The CARDIA Brain MRI Study.
Not available
S-EPMC5949318 | biostudies-literature
TranscriptomicsRegulon prediction of the sporulation factors Spo0A, SigF, SigE, and SigG in Clostridium acetobutylicum ATCC 824
Clostridium acetobutylicum, the endospore-forming anaerobe best known for its ABE (acetone-butanol-ethanol) fermentation, has received renewed attention recently for the biological production of butanol, both for bulk chemical production and as a potential biofuel. With butanol production in mind, m...
ORGANISM(S): Clostridium acetobutylicum ATCC 824 
2011-02-28 | E-GEOD-24103 | biostudies-arrayexpress
TranscriptomicsGenotyping of human diagnosic AML samples reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias
Genome-wide analysis of single nucleotide polymorphisms in 64 acute myeloid leukemias has revealed that 20% exhibited large regions of homozygosity that could not be accounted for by visible chromosomal abnormalities in the karyotype. Further analysis confirmed that these patterns were due to partia...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7490 | biostudies-arrayexpress
TranscriptomicsIdentification of novel sub-microscopic copy number aberrations in adult acute myeloid leukemia
In this study we have screened 56 pairs of AML samples for cryptic copy number aberration and loss-of-heterozygosity. We have identified 80 CNAs among 56 patient samples; 21 containing <5 genes while 11 contained or were present within a single gene. Four (7%) patients carried gains at sub-telomeres...
ORGANISM(S): Homo sapiens 
2012-03-08 | E-GEOD-20672 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for low-grade astrocytoma samples
Copy number analysis of 21 paediatric low-grade astrocytomas identified a discrete copy number gain of 1.9Mb in chromosome band 7q34. The gain was present in 12/14 cerebellar pilocytic astrocytomas. Subsequent analysis of tumour cDNA indentified a novel gene fusion between KIAA1549 and BRAF in these...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-14960 | biostudies-arrayexpress
TranscriptomicsHigh-resolution genetic analysis of cancer cell lines with near normal karyotypes
Cancer development is associated with multiple genetic alterations and genomic instability either at the chromosomal or base pair level is generally thought to underlie these changes. However, it is still unknown whether genetic instability is absolutely required for tumorigenesis. Here we investig...
ORGANISM(S): Homo sapiens 
2008-03-14 | E-GEOD-8649 | biostudies-arrayexpress
TranscriptomicsHigh-resolution genome-wide copy-number analysis suggests a monoclonal origin of multi-focal prostate cancer
Many human cancers present as multi-focal lesions. Understanding the clonal origin of multi-focal cancers is of both etiological and clinical importance. The molecular basis of multi-focal prostate cancer has previously been explored using only a limited number of isolated markers and, although inde...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-GEOD-29569 | biostudies-arrayexpress
UnknownThe Type and Amount of Dietary Fat Affect Plasma Factor VIIc, Fibrinogen, and PAI-1 in Healthy Individuals and Individuals at High Cardiovascular Disease Risk: 2 Randomized Controlled Trials.
Not available
S-EPMC7398773 | biostudies-literature
GenomicsATD
WTCCC1 project Autoimmune Thyroid Disease (ATD) samples
EGAD00000000011 | EGA
GenomicsBC
WTCCC1 project Breast cancer (BC) samples
EGAD00000000013 | EGA
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