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Biofilms with immobilized cells in industrial fermentation are beneficial. Encased in extracellular polymeric substance, cells forming biofilms are regulated by various factors. Nitric oxide (NO), as a signaling molecule, recognized as quorum sensing molecule regulating microbe biofilm formation. Re...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-11-12 | PXD010751 | Pride
The transcription factor Mac1 is a key regulator of copper homeostasis and controls the transcriptional response to copper-limiting conditions in fungi. Expression analyses performed in the soil-borne plant pathogen Fusarium oxysporum revealed that almost all copper starvation-induced genes are down...
ORGANISM(S): Fusarium oxysporum f. sp. lycopersici 4287 
2024-11-07 | GSE244102 | GEO
Role of Mac1 in gene regulation under copper limiting conditions in Fusarium oxysporum [ChIP-seq]
The transcription factor Mac1 is a key regulator of copper homeostasis, controlling the transcriptional response to copper-limiting conditions in fungi. It has been described as a virulence factor in human pathogens such as Candida albicans and Aspergillus fumigatus, but surprisingly its role in pla...
ORGANISM(S): Fusarium oxysporum f. sp. lycopersici 4287 
2024-11-07 | GSE243247 | GEO
Effect of Mac1 deletion on copper homoestasis and virulence in Fusarium oxysporum f. sp. lycopersici [RNA-seq]
Primary hematopoietic cells from mouse bone marrow were sorted and hybridised expression microarrays as part of a study investigating the differentiation of a multipotential cell-line to erthroid and myeloid fates. We used the paradigmatic 'GATA-PU.1 axis’ to explore, at systems-level, dynamic relat...
ORGANISM(S): Mus musculus 
Genomics
Copper- and Mac1-dependent transcriptome of Histoplasma capsulatum yeast
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