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MetabolomicsTranscriptomic and metabolomic analyses reveal the differential accumulation of phenylpropanoids and terpenoids in hemp autotetraploid and its diploid progenitor

Background

Cannabis sativa, a dioecious plant that has been cultivated worldwide for thousands of years, is known for its secondary metabolites, especially cannabinoids, which possess several medicinal effects. In this study, we investigated the autopolyploidization effects on the biosynthes...
2023-09-21 | MTBLS6032 | MetaboLights
MetabolomicsIntegrated lipidomic and transcriptomic analysis uncovers the lipid dynamic changes in Camellia weiningensis during seed development

Oil-tea Camellia is a promising woody oil crop that has been widely used as a cooking oil, lubricant, and cosmetics. However, there is a lack of dominant varieties suitable for high-altitude cold mountainous regions. Camellia weiningensis (C. weiningensis) is the only h...

2026-01-27 | MTBLS13636 | MetaboLights
MetabolomicsIntegrated transcriptomic and metabolomic analysis reveals insights into drought stress in Plantago lanceolata
Background: The unique vertical climate of Yunnan Province provides diverse resources for livestock development; however, frequent seasonal droughts during winter and spring result in a severe imbalance between forage supply and demand, constituting a major bottleneck for sustainable pastoral agricu...
2026-05-06 | MTBLS14435 | MetaboLights
MetabolomicsIntegrated transcriptomic and metabolomic analyses reveal the mechanism by which quercetin inhibits reflux esophagitis in rats

Quercetin relieves symptoms in mice with reflux esophagitis (RE), but the mechanism is unclear. Quercetin attenuates esophageal mucosal inflammation in RE mice by inhibiting the production of inflammatory factors IL-β and IL-6. In addition, using transcriptomic and metabolomic analyses, we found ...

2025-04-03 | MTBLS12138 | MetaboLights
MetabolomicsA comprehensive metabonomic and transcriptomic analysis reveals how inhibiting glycolysis affects regulatory T cell proliferation

Background: Blocking glycolysis inhibits regulatory T cells (Tregs), which are often hijacked by tumor cells whose survival relies on glycolysis to inhibit antitumor immunity. However, how glycolysis influences Treg proliferation/differentiation remains unclear. Monocarboxylate transporters (MCTs...

2024-08-06 | MTBLS8002 | MetaboLights
MetabolomicsIntegrated transcriptomic and metabolomic analysis reveals the metabolic programming of GM-CSF-and M-CSF-differentiated mouse macrophages

Macrophages play a critical role in the inflammatory response and tumor development. Macrophages are primarily divided into pro-inflammatory M1-like and anti-inflammatory M2-like macrophages based on their activation status and functions. In vitro macrophage models could be derived from ...

2023-09-19 | MTBLS6502 | MetaboLights
MetabolomicsDrought Stress-Induced Physiological and Molecular Changes in Strawberries: An Integrated Transcriptomic and Metabolomic Perspective

This study identifies drought-responsive differential metabolites in two strawberry cultivars ('Benihoppe' and 'Kaorino') via metabolomics, uncovering their genotype-specific metabolic mechanisms of drought tolerance. It provides metabolic-level evidence for breeding drought-resistant strawberrie...

2025-11-22 | MTBLS13366 | MetaboLights
MetabolomicsIntegrative transcriptomic, metabolomic, and physiological analyses reveal the root adaptive mechanisms of common vetch (Vicia sativa L.) under drought stress
Drought is a major abiotic stress that limits the productivity and ecological adaptability of leguminous forage crops. As the primary organs that sense soil water deficits, roots play an essential role in plant adaptation to drought. Common vetch (Vicia sativa L.) is an important annual leguminous f...
2026-07-27 | MTBLS15164 | MetaboLights
GenomicsTranscriptomic changes upon ABA treatment dependent on VND transcription factors
Transcriptomic changes upon ABA treatment dependent on VND transcription factors
PRJNA716333 | ENA
TranscriptomicsConnexin-dependent transcellular transcriptomic networks in mouse brain
Microarray experiments have generally focused on magnitude of gene expression changes in pathological conditions, thereby using the method as a high throughput screen to identify candidate marker genes and/or to validate phenotypic differences. We have used novel strategies to extract additional in...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-6355 | biostudies-arrayexpress
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