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Given that foliar diseases severely impact tea yield and quality, and prior research has shown that CsCHS1 positively regulates resistance to Didymella segeticola in tea leaves, we performed metabolomics analysis on tea leaves with transient overexpression of CsCHS1 to investigate the metabolites...

2026-09-08 | MTBLS13309 | MetaboLights

1. The ecological niche of aphids is largely defined by the phloem sap of plants, which they consume. Previous studies revealed that aphids may change the phloem sap metabolome and that a previous aphid infestation may benefit them. As aphids reproduce parthenogenetically, the performance and pre...

2025-02-25 | MTBLS7626 | MetaboLights
Fetuses respond to transient hypoxia (a common stressor in utero) with cellular responses that are appropriate for promoting survival of the fetus. The present experiment was performed to identify the acute genomic responses of the fetal hypothalamus to transient hypoxia. Three fetal sheep were ex...
ORGANISM(S): Ovis aries 
Transient leukemia (TL) is evident in 5-10% of all neonates with Down syndrome (DS) and associated with N-terminal truncating GATA1-mutations (GATA1s). Here we analyzed the effect of on gene expression upon ectopic expression of Gata1s or Gata1, while simultaneously knocking down endogenous GATA1,...
ORGANISM(S): Homo sapiens 
This SuperSeries is composed of the SubSeries listed below. Repetitive sequences such as telomeres, centromeres, and retrotransposons are packed in permanently-condensed and transcriptionally-silenced heterochromatin, whose maintenance is critical for the genome stability. We have recently found th...
ORGANISM(S): Mus musculus 
Here, we apply differential transcriptome analysis on microscopically isolated cell populations, to define five transcriptional programs that represent each transient embryonic zone and the progression between these zones. The five transcriptional programs contain largely uncharacterized genes in ad...
ORGANISM(S): Mus musculus 
Comparison of transient myeloproliferative disorder and acute megakaryoblastic leukaemia in Down syndrome.
ORGANISM(S): Homo sapiens 
During Epithelial-Mesenchymal Transition (EMT), apical-basal polarized epithelial cells are converted to front-to-back polarized mesenchymal cells that only form loose cell-cell adhesions. These phenotypic changes are accompanied by acquisition of increased motility and invasiveness. EMT programs ar...
ORGANISM(S): Homo sapiens 
We report the immediate effects of estrogen signaling on the transcriptome of breast cancer cells using Global Run-On and sequencing (GRO-seq). We found that estrogen signaling directly regulates a strikingly large fraction of the transcriptome in a rapid, robust, and unexpectedly transient manner. ...
ORGANISM(S): Homo sapiens 
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