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UnknownTranslation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.
Not available
S-EPMC3836723 | biostudies-literature
UnknownEnabling stop codon read-through translation in bacteria as a probe for amyloid aggregation.
Not available
S-EPMC5605706 | biostudies-literature
TranscriptomicsDistinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments
During translation elongation, the ribosome ratchets along its mRNA template, incorporating each new amino acid and translocating from one codon to the next. The elongation cycle requires dramatic structural rearrangements of the ribosome. We show here that deep sequencing of ribosome-protected mRNA...
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-10 | E-GEOD-58321 | biostudies-arrayexpress
UnknownTranslational read-through of a nonsense mutation in ATP7A impacts treatment outcome in Menkes disease.
Not available
S-EPMC2917729 | biostudies-literature
UnknownAtaluren and aminoglycosides stimulate read-through of nonsense codons by orthogonal mechanisms.
Not available
S-EPMC7812769 | biostudies-literature
TranscriptomicsRibosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster
Ribosomes can read through stop codons in a regulated manner, elongating rather than terminating the nascent peptide. Stop codon readthrough is essential to diverse viruses, and phylogenetically predicted to occur in a few hundred genes in Drosophila melanogaster, but the importance of regulated rea...
ORGANISM(S): Drosophila melanogaster 
2013-12-05 | E-GEOD-49197 | biostudies-arrayexpress
UnknownDegradation of Stop Codon Read-through Mutant Proteins via the Ubiquitin-Proteasome System Causes Hereditary Disorders.
Not available
S-EPMC4653699 | biostudies-literature
GenomicsTLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR
TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR
PRJNA1032595 | ENA
TranscriptomicsRoles for Transcript Leaders in Translation and mRNA Decay Revealed by Transcript Leader Sequencing
Transcript leaders (TLs) can have profound effects on mRNA translation and stability. To map TL boundaries genome-wide, we developed TL-Sequencing (TL-Seq), a technique combining enzymatic capture of m7G-capped mRNA 5'-ends with high-throughput sequencing. TL-Seq identified mRNA start sites for the ...
ORGANISM(S): Saccharomyces cerevisiae 
2013-04-03 | E-GEOD-39074 | biostudies-arrayexpress
UnknownTranslational read-through promotes aggregation and shapes stop codon identity.
Not available
S-EPMC7144920 | biostudies-literature
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