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MetabolomicsTranslational repression of viral RNA mediates arbovirus persistence in mosquitoes

Persistent infection of mosquito vectors is essential for the transmission of arboviruses, yet how these viruses produce sufficient progeny without compromising host cell fitness remains unclear. Arbovirus genomes exhibit suboptimal codon usage for both human and mosquito hosts, raising questions...

2026-02-12 | MTBLS12760 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (A)
Translational genomics, the use of model species to generate knowledge about biological processes and the functions of genes, offers great promise to biotechnologists. Few studies have sought robust responses of model plants to environmental stresses, such as salinity, by altering the stress dosage ...
2015-09-14 | MTBLS43 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (C)
Translational genomics, the use of model species to generate knowledge about biological processes and the functions of genes, offers great promise to biotechnologists. Few studies have sought robust responses of model plants to environmental stresses, such as salinity, by altering the stress dosage ...
2015-09-14 | MTBLS54 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on the model legume Lotus japonicus (B)
Translational genomics, the use of model species to generate knowledge about biological processes and the functions of genes, offers great promise to biotechnologists. Few studies have sought robust responses of model plants to environmental stresses, such as salinity, by altering the stress dosage ...
2015-09-14 | MTBLS44 | MetaboLights
MetabolomicsLong-lasting effects of oral polysaccharides on chemotherapy efficacy via alteration of the gut microbiota in a mouse model

Gemcitabine always has a short-term immune effect, and we consider using oral polysaccharides to lengthen its immune effect by modulating gut microbiotas. To verify this, we built a breast cancer mice model in situ, oral polysaccharides and a low-dose of Gemcitabine were administrated, ...

2025-06-14 | MTBLS12563 | MetaboLights
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in uninfected, resolved and chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36533 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Liver gene expression in tumor and non-tumor samples from chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36545 | biostudies-arrayexpress
UnknownThe Translational Science Benefits Model: A New Framework for Assessing the Health and Societal Benefits of Clinical and Translational Sciences.
Not available
S-EPMC5759746 | biostudies-literature
TranscriptomicsTranscriptomic analysis of the woodchuck model of chronic hepatitis B: Kidney gene expression in uninfected, resolved and chronically infected woodchucks
The Eastern woodchuck (Marmota monax) is naturally infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to the human hepatitis B virus (HBV). The woodchuck is used as an animal model for studying chronic hepatitis B (CHB) and HBV-associated hepatocellular carcinoma (HCC) in ...
ORGANISM(S): Marmota monax 
2012-04-10 | E-GEOD-36541 | biostudies-arrayexpress
TranscriptomicsTranscrition profiling of shoots from related model and cultivated Lotus plant species following salt acclimation
Many plant researchers have applied genomic tools to model species to identify abiotic stress responsive genes that might be useful for improving stress tolerance in crops. However, it is unclear whether this translational approach will be successful given the complexity of abiotic stress tolerance....
ORGANISM(S): Lotus corniculatus 
2010-08-10 | E-MEXP-2344 | biostudies-arrayexpress
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