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MetabolomicsB-cell Translocation Gene 2 Inhibits UFMylation Modification of FMO1 thus Restricting Taurine Synthesis and Exacerbating Ferroptosis in Hepatic Ischemia-Reperfusion Injury

Hepatic ischemia-reperfusion (I/R) injury is a common complication occurs during liver transplantation. However, the mechanisms underlying hepatic I/R injury have not been fully elucidated. B-cell translocation gene 2 (Btg2) has been implicated in the development of various diseases. However, its...

2026-03-07 | MTBLS11677 | MetaboLights
GenomicsTriticum aestivum/Dasypyrum villosum translocation line
Triticum aestivum/Dasypyrum villosum translocation line Assembly
PRJNA700793 | ENA
GenomicsERCC6L2 suppresses chromosome translocation
ERCC6L2 suppresses chromosome translocation
PRJNA1184159 | ENA
TranscriptomicsDifferential Expression of NF-kB target genes in MALT lymphoma with and without chromosome translocation
MALT lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH and t(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway. Gastric MALT lymphomas harboring such translocation do not respond to H. pylori eradication, while those without translocation can be...
ORGANISM(S): Homo sapiens 
2010-05-31 | E-GEOD-18736 | biostudies-arrayexpress
TranscriptomicsGeneration of NPM1-ALK translocation in human T lymphocytes faithfully recapitulates the diversity of ALK+ ALCL tumor phenotype
To recapitulate the t(2;5)(p23;q35) chromosomal translocation, activated T lymphocytes from healthy donors PBMC were transfected with the RNP complex composed of the protein Cas9 with gRNA NPM1 (targeting NPM1 gene) and gRNA ALK (targeting ALK gene). Control cells were wild-type CD4+ activated lymp...
ORGANISM(S): Homo sapiens 
2022-02-09 | E-MTAB-10924 | biostudies-arrayexpress
ModelsTomida2003 - Calcium Oscillatory-induced translocation of nuclear factor of activated T cells
Tomida2003 - NFAT functions Calcium Oscillation This model is described in the article: NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation. Tomida T, Hirose K, Takizawa A, Shibasaki F, Iino M. EMBO J. 2003 Aug; 22(15): 3825-3832 Abstract: ...
2024-09-02 | BIOMD0000000678 | BioModels
GenomicsGCB subtype DLBCL with BCL2 translocation
GCB subtype DLBCL with BCL2 translocation
PRJNA744546 | ENA
GenomicsTranslocation breakpoint in yeast
Translocation breakpoint in the genome of a wine making yeast
PRJEB4706 | ENA
TranscriptomicsDifferences Between Follicular Lymphoma With and Without Translocation t(14;18)
Follicular lymphoma (FL) is genetically characterized by the presence of the t(14;18)(q32;q21) chromosomal translocation in approximately 90% of cases. In contrast to FL carrying the t(14;18), their t(14;18)-negative counterparts are less well studied regarding their immunohistochemical, genetic, mo...
ORGANISM(S): Homo sapiens 
2009-06-02 | E-GEOD-16131 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human Rhabdomyosarcoma biopsy samples (15 embryonal RMS, 10 translocation-positive alveolar RMS and 5 translocation-negative alveolar RMS)
We measured the expression profiles of a series of 30 Rhabdomyosarcoma biopsy samples (15 embryonal RMS, 10 translocation-positive alveolar RMS and 5 translocation-negative alveolar RMS). Expression data was used for unsupervised hierarchical clustering as well as supervised analysis to find gene ex...
ORGANISM(S): Homo sapiens 
2004-06-30 | E-MEXP-121 | biostudies-arrayexpress
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