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MetabolomicsProteolytic-Resistant Self-Assembling Peptide Nanofibers Combat Specific Bacterial Infections via Trap-and-Kill

The rise in global antibiotic resistance highlights the urgent need for effective antimicrobial agents. Antimicrobial peptides (AMPs) offer a potential solution to combat bacterial resistance. However, key challenges remain in addressing the limitations of current peptide drugs and biomaterials, ...

2025-06-13 | MTBLS12424 | MetaboLights
TranscriptomicsEvaluation of TRAP-sequencing technology with a versatile conditional mouse model
Evaluation of TRAP-sequencing by comparing transcriptomes and translatomes of different organs and distinct cell populations. E14.5 brain and kidney transcriptome and translatome profiling of organs or distinct cell populations from these organs was performed using the Illumina TruSeq RNA technology...
ORGANISM(S): Mus musculus 
2013-10-28 | E-GEOD-51619 | biostudies-arrayexpress
TranscriptomicsNovel primate miRNAs co-evolved with ancient target genes in germinal zone specific expression patterns [RISC trap immunoprecipitation]
Major non primate-primate differences in corticogenesis include the dimensions, precursor lineages and developmental timing of the germinal zones (GZ). microRNAs (miRNAs) of laser dissected GZ compartments and cortical plate (CP) from embryonic E80 macaque visual cortex were deep sequenced. The CP a...
ORGANISM(S): Homo sapiens 
2014-02-27 | E-GEOD-52607 | biostudies-arrayexpress
TranscriptomicsTrap-80-dependence of TNF-alpha-induced genes
In fibroblasts, p65-dependent genes can be sub-divided, depending on whether they are Trap-80-dependent or -independent. To examine the generality of this grouping, we performed a microarray analysis of wild-type and Trap-80 knock-down fibroblasts, before and after stimulation of NF-kappaB activity...
ORGANISM(S): Mus musculus 
2010-04-09 | E-GEOD-12697 | biostudies-arrayexpress
GenomicsPrenociceptin TRAP
Prenociceptin TRAP
PRJNA428727 | ENA
TranscriptomicsEffect of telmisartan on prostate carcinogenesis in TRAP rats
We investigate the direct effects of ARBs on prostate cancer growth and progression. A total of 36 heterozygous male TRAP rats of 3 weeks of age were randomly divided into three groups. Rats in group 1 as a control received basal diet and tap water. The rats in groups 2 and 3 continuously received 2...
ORGANISM(S): Rattus norvegicus 
2011-07-30 | E-GEOD-29445 | biostudies-arrayexpress
TranscriptomicsTruncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line
Many thousand long non-coding (lnc) RNAs are mapped in the human genome. Time consuming studies using reverse genetic approaches by post-transcriptional knock-down or genetic modification of the locus demonstrated diverse biological functions for a few of these transcripts. The Human Gene Trap Mutan...
ORGANISM(S): Homo sapiens 
2015-12-22 | E-GEOD-71284 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis plants with the chlorophyll removed by combining enhancer trap and RNAi approaches
Chlorophyll was removed from the veins of the C3 plant Arabidopsis by combining enhancer trap and RNAi approaches. Three independent transgenic lines were created. These were each compared to the parent line, J1511, in a microarray experiment.
ORGANISM(S): Arabidopsis thaliana 
2009-12-01 | E-MEXP-1988 | biostudies-arrayexpress
TranscriptomicsVentral prostate in TRAP rats: Control vs. apocyin treatment
The gene expression profling between Control and apocynin 500 mg/L treatment in ventral prostate lobe of Transgenic Rat for Adenocarcinoma of Prostate (TRAP) rats Two-condition experiment, Control vs. apocynin treatment. Biological replicates: 3 control rats, 3 apocynin-treated rats. Mixed 3 sample...
ORGANISM(S): Rattus norvegicus 
2013-10-18 | E-GEOD-47200 | biostudies-arrayexpress
GenomicsFlorida Swarm Trap Project
Florida Swarm Trap Project Raw sequence reads
PRJNA1477635 | ENA
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