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TranscriptomicsSingle-cell transcriptomics reveals receptor transformations during olfactory neurogenesis
We report RNA sequencing of single olfactory neurons from mouse olfactory epithelium in developmental progression from progenitors to precursors to immature neurons to mature neurons. Most mature neurons expressed only one of ~ 1000 odorant receptor genes (Olfrs) at high levels, whereas many immatur...
ORGANISM(S): Mus musculus 
2015-11-25 | E-GEOD-75413 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs regulate adipogenesis
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-29899 | biostudies-arrayexpress
UnknownTopHat: discovering splice junctions with RNA-Seq.
Not available
S-EPMC2672628 | biostudies-literature
TranscriptomicsThe effect of knockdown Abl kinases on breast cancer cells' global transcriptome
To gain insight into the signaling pathway(s) required for ABL1/ABL2-dependent bone metastasis, we evaluated the consequences of single or double inactivation of ABL1 and ABL2 on the transcriptome of breast cancer cells. Double ABL1/ABL2 knockdown was required to decrease the levels of p-CrKL by mor...
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-69125 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human BR.1N and HaCaT cell lines treated with zebularine against untreated controls
The experimental design demonstrates that zebularine, a DNA methyltransferase inhibitor, promotes regeneration in the mouse and that retinoic acid and zebularine synergistically accelerate this process.
ORGANISM(S): Homo sapiens 
2019-11-02 | E-MTAB-6832 | biostudies-arrayexpress
TranscriptomicsA cell competition-based drug screen identifies a novel compound that targets c-Myc addiction of leukemia cells
Purpose: BCR-ABL-positive acute lymphoid leukemia (ALL) has a dire prognosis. Despite improved disease-free survival due to implementation of TKIs in front-line therapy, patient survival remains unsatisfactory and there exists a need for new treatments. Therefore, we performed a drug screen based on...
ORGANISM(S): Mus musculus 
2020-12-07 | GSE100678 | GEO
TranscriptomicsRNA-seq of human ASCs expanded with 10% FBS and in FBS-deprived condition
In this experiment we determined the effects of FBS supplementation and subsequent deprivation (after second passage) on the whole transcriptome, including comprehensive mRNA and miRNA profiling.
ORGANISM(S): Homo sapiens 
2018-08-09 | E-MTAB-6436 | biostudies-arrayexpress
TranscriptomicsDifferential analysis of gene regulation at transcript resolution by RNA-Seq
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-12-11 | E-GEOD-37704 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Aspergillus fumigatus infected to HL-60 derived macrophage-like cells for 0,1, and 2 hours.
Purpose : The goals of this study are to compare transcriptome profiling (RNA-seq) of Aspergillus fumigatus infected to macrophage-like cells for 0, 1 and 2 hours. Method : HL-60 cells were cultured in RPMI 1640 medium containing 10% fetal bovine serum (FBS) and 1% Gibco™ Antibiotic-Antimycotic at 3...
ORGANISM(S): Aspergillus fumigatus 
2019-08-15 | GSE135818 | GEO
TranscriptomicsIntegrative Annotation of Human Large Intergenic Non-Coding RNAs Reveals Global Properties and Specific Subclasses
Large intergenic non-coding RNAs (lincRNAs) are emerging as key regulators of diverse cellular processes. Determining the function of individual lincRNAs remains a challenge. Recent advances in RNA sequencing (RNA-Seq) and computational methods allow for an unprecedented analysis of such transcripts...
ORGANISM(S): Homo sapiens 
2011-08-27 | E-GEOD-30554 | biostudies-arrayexpress
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