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MetabolomicsMetabolomic Profiles of Recovery from Traumatic Brain Injury
Not available
ORGANISM(S): Homo sapiens 
ST000721 | MetabolomicsWorkbench
MetabolomicsDiscovery of Lipidome Alterations Following Traumatic Brain Injury via High-Resolution Metabolomics
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ORGANISM(S): Rattus norvegicus 
ST000920 | MetabolomicsWorkbench
ProteomicsGFAP and MBP peptides in Traumatic Brain Injury
Glial fibrillary acidic protein (GFAP) is the major intermediate filament III protein of astroglia cells and is upregulated in astrogliosis following traumatic brain injury (TBI). Here we reported that GFAP is truncated at both the C- and N-terminals by cytosolic protease calpain to GFAP breakdown p...
ORGANISM(S): Homo Sapiens 
PXD026550 | panorama
MetabolomicsLipidome Alterations Following Mild Traumatic Brain Injury.
Not available
ORGANISM(S): Rattus norvegicus 
ST001950 | MetabolomicsWorkbench
TranscriptomicsGene expression profiles after traumatic brain injury
Time dependent-profiles in the gene expression level following lateral moderate fluid percussion injury in the rat brain We used microarray to elucidate relationship between the alteration of gene expression levels and the progression of brain damages following traumatic brain injury. To examine the...
ORGANISM(S): Rattus norvegicus 
2010-12-07 | E-GEOD-24047 | biostudies-arrayexpress
MetabolomicsMolecular Docking and Dynamic Study of Ethanol Extract of Citrus sinensis as Keap-1 and NMDA inhibitor in Brain Injury

Traumatic brain injury is a significant cause of mortality in young adults and disability in all age groups. Secondary injury involving various processes such as oxidative stress, which induced neuronal apoptosis, ensued afterward. This study aimed to analyze the active compounds of Citrus sinens...

2023-01-02 | MTBLS5785 | MetaboLights
ProteomicsLFQ proteomics of isolated GABAergic interneurons from mouse models of traumatic brain injury
Posttraumatic epilepsy (PTE) is a major public health concern and strongly contributes to human epilepsy cases worldwide. However, their effective treatment and prevention remains a matter of intense research. The present study provides new insights into the GABAA-receptor-stabilizing protein ubiqui...
ORGANISM(S): Mus Musculus (mouse) 
2022-07-14 | PXD031368 | JPOST Repository
TranscriptomicsTranscriptome profiling in the DA and PVG inbred rat strains after traumatic brain injury
Genetic factors are believed to be of importance for outcome of traumatic brain injury (TBI). However, so far mainly allelic variation in apolipoprotein E4 has been studied in human TBI. In order to study the role of genetic factors in experimental TBI, we examined parental DA and PVG strains before...
ORGANISM(S): Rattus norvegicus 
2012-09-06 | E-MTAB-795 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice and rats at different time points after moderate levels of brain injury to identify candidate molecular pathways induced by brain injury.
Summary: Brain trauma is a major cause of morbidity and mortality, both in adult and pediatric populations. Much of the functional deficit derives from delayed cell death resulting from induction of neurotoxic factors that overwhelm endogenous neuroprotective responses. Hypothesis: Gene expression p...
ORGANISM(S): Rattus norvegicus 
2007-11-22 | E-GEOD-2392 | biostudies-arrayexpress
TranscriptomicsRNA-seq of mouse brain tissue repopulating microglia in response to traumatic brain injury
We assessed the roles of repopulating microglia in brain repair using mouse models. In this project, we show that removal of microglia from the mouse brain has little impact on the outcome of TBI but inducing the turnover of these cells through either pharmacologic or genetic approaches can yield a ...
ORGANISM(S): Mus musculus 
2020-02-15 | E-MTAB-8765 | biostudies-arrayexpress
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