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TranscriptomicsTranscription profiling by array of human gangliogliomas and adjacent tissue
Gangliogliomas, the most frequent neoplasms in patients with pharmacoresistant focal epilepsies, are characterized by histological combinations of glial and dysplastic neuronal elements, a highly differentiated phenotype and rare gene mutations.

Here, we have used discrete microdissected gang...
ORGANISM(S): Homo sapiens 
2008-10-03 | E-MEXP-1690 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast Gcn4 and Arr1 deletion mutant as well as Gcn4 Arr1 double deletion mutant.
Transcription profiling of wild type yeast strain as well as strains carrying a deletion of Gcn4, Arr1 or both. Gene expression in rich medium (YPD) and under osmotic stress conditions (YPD + 0.8M NaCl) was compared.
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-25 | E-MEXP-3566 | biostudies-arrayexpress
TranscriptomicsPeriodic mRNA synthesis and degradation co-operate during cell cycle gene expression
Dynamic transcriptome profiling with metabolic labeling (4tU) (Sun et al. Genome Research 2012) was applied to synchronized S.cerevisiae cells to estimate labeled and total mRNA levels every 5 minutes for three complete cell cycles. The dataset comprises two time series from independent biological r...
ORGANISM(S): Saccharomyces cerevisiae 
2014-02-04 | E-MTAB-1908 | biostudies-arrayexpress
TranscriptomicsMC EMiNEM Maps the Interaction Landscape of the Mediator
By applying MC EMiNEM (a novel method based on the concept of Nested Effects Models (NEMs) for the retrieval of functional dependencies between proteins that have pleiotropic effects on mRNA transcription) to the expression data from four gene perturbation studies (three of them unpublished) in Sacc...
ORGANISM(S): Saccharomyces cerevisiae 
2012-06-01 | E-MTAB-1037 | biostudies-arrayexpress
TranscriptomicsDynamic transcriptome analysis of osmotic stress response
Dynamic transcriptome analysis of osmotic stress response. Unperturbed RNA synthesis and decay rates can be obtained via metabolic RNA labeling and kinetic modeling (Cleary et al, 2005; Kenzelmann et al, 2007; Dolken et al, 2008; Friedel and Dolken, 2009; Miller et al, 2009). The nucleoside analog 4...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-08 | E-MTAB-1059 | biostudies-arrayexpress
TranscriptomicsDynamic transcriptome analysis reveals mRNA synthesis and decay in yeast
To obtain rates of mRNA synthesis and decay in yeast, we established dynamic transcriptome analysis (DTA). DTA combines non-perturbing metabolic RNA labeling with dynamic kinetic modeling. DTA was used to monitor the cellular response to osmotic stress in comparison to the wild type. Genomic occupa...
ORGANISM(S): Saccharomyces cerevisiae 
2011-11-01 | E-MTAB-439 | biostudies-arrayexpress
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