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TranscriptomicsSigma factor E of Mycobacterium tuberculosis controls the expression of bacterial components that modulate macrophages
Sigma factor E (SigE) controls the expression of genes that are essential for Mtb virulence. In this work, we have identified the SigE regulon during infection of macrophages Our results indicate that SigE regulates the expression of genes involved in the maintenance of Mtb cell envelope integrity a...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-25 | E-GEOD-7962 | biostudies-arrayexpress
TranscriptomicsThe sigma factor E of Mycobacterium tuberculosis modulates the inflammatory response of macrophages
Mycobacterium tuberculosis (Mtb) is well adapted to survive in macrophages and usually subverts the bactericidal mechanisms of these professional phagocytes. The adaptation of Mtb to the intracellular life depends on its ability to regulate the expression of its genes. Among the most important bact...
ORGANISM(S): Mus musculus 
2010-05-25 | E-GEOD-7871 | biostudies-arrayexpress
TranscriptomicsThe sigma factor E of Mycobacterium tuberculosis modulates the inflammatory response of human THP1 cells
Mycobacterium tuberculosis (Mtb) is well adapted to survive in macrophages and usually subverts the bactericidal mechanisms of these professional phagocytes. The adaptation of Mtb to the intracellular life depends on its ability to regulate the expression of its genes. Among the most important bact...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-7870 | biostudies-arrayexpress
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