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GenomicsEnhancer-associated H3K4 mono-methylation by Drosophila Trithorax-related, the Drosophila homolog of Mll3/Mll4
Mono-methylation of histone H3 on lysine 4 (H3K4me1) and acetylation of histone H3 on lysine 27 (H3K27ac) are histone modifications that are highly enriched over the body of actively transcribed genes and enhancers. Although in yeast all H3K4 methylation patterns including H3K4me1 are implemented by...
ORGANISM(S): Mus musculus 
2012-12-01 | E-GEOD-41440 | biostudies-arrayexpress
GenomicsGenome-wide binding of WDR5 and GRHL3
The antagonistic actions of Polycomb and Trithorax are responsible for proper cell fate determination in mammalian tissues. In the epidermis, a self-renewing epithelium, previous work has shown that release from Polycomb repression only partially explains differentiation gene activation. We now show...
ORGANISM(S): Homo sapiens 
2012-11-10 | E-GEOD-42180 | biostudies-arrayexpress
GenomicsLoss of H3K27 monomethylation leads to DNA-methylation-independent release of gene silencing
Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications including DNA methylation, histone 3 dimethylation at lysine 9 (H3K9me2), and monomethylation at lysine 27 (H3K27me1). The enzymes catalyzing DNA methylation and H3K9me2 have been identified and muta...
ORGANISM(S): Arabidopsis thaliana 
2009-05-31 | E-GEOD-16071 | biostudies-arrayexpress
GenomicsFunctional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ES cells
The Polycomb repressive complexes PRC1 and PRC2 are key mediators of heritable gene silencing in multicellular organisms. Here we characterize AEBP2, a known PRC2 cofactor which, in vitro, has been shown to stimulate PRC2 activity. We show that AEBP2 localises specifically to PRC2 target loci, incl...
ORGANISM(S): Mus musculus 
2016-08-02 | E-GEOD-83082 | biostudies-arrayexpress
UnknownA cytoplasm-specific activity encoded by the Trithorax-like ATX1 gene.
Not available
S-EPMC3113559 | biostudies-literature
UnknownTranscriptional network controlled by the trithorax-group gene ash2 in Drosophila melanogaster.
Not available
S-EPMC152285 | biostudies-literature
UnknownTrithorax and ASH1 interact directly and associate with the trithorax group-responsive bxd region of the Ultrabithorax promoter.
Not available
S-EPMC84613 | biostudies-literature
TranscriptomicsATX1_apex
Analysis of the gene expression profile of the atx1 mutant of Arabidopsis thaliana compared to the wild-type, using apices tissue of in in vitro plants and Affymetrix ATH1 chips.
ORGANISM(S): Arabidopsis thaliana 
2006-06-01 | E-MEXP-502 | biostudies-arrayexpress
GenomicsPolycomb and trithorax epigenetic marks regulate temperature response in the phytoplanktonic microalgae Ostreococcus tauri [RNA-seq]
Polycomb and trithorax epigenetic marks regulate temperature response in the phytoplanktonic microalgae Ostreococcus tauri [RNA-seq]
PRJNA995501 | ENA
GenomicsPolycomb and trithorax epigenetic marks regulate temperature response in the phytoplanktonic microalgae Ostreococcus tauri [ChIP-seq]
Polycomb and trithorax epigenetic marks regulate temperature response in the phytoplanktonic microalgae Ostreococcus tauri [ChIP-seq]
PRJNA995502 | ENA
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