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TranscriptomicsDeep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3' Trailers
Background: MicroRNAs (miRNAs) are 22-nt small non-coding regulatory RNAs that have generally been considered to regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent studies have reported that some miRNAs localize to and function in the nucleus. Methodology/Pr...
ORGANISM(S): Homo sapiens 
2010-07-14 | E-GEOD-22918 | biostudies-arrayexpress
TranscriptomicsRNA-seq mouse development
The genetic code is an abstraction of how mRNA codons and tRNA anticodons molecularly interact during protein synthesis; the stability and regulation of this interaction remains largely unexplored. Here, we quantitatively characterized the expression of mRNA and tRNA genes across developing mouse ti...
ORGANISM(S): Mus musculus 
2014-08-08 | E-MTAB-2328 | biostudies-arrayexpress
GenomicsTransfer RNA pools in human cells are controlled by selective gene expression [tRNA-Seq]
Transfer RNA pools in human cells are controlled by selective gene expression [tRNA-Seq]
PRJNA947527 | ENA
GenomicsYAMAT-seq of mature tRNA pools in the bacterium Pseudomonas fluorescens SBW25 and derivatives
YAMAT-seq of mature tRNA pools in the bacterium Pseudomonas fluorescens SBW25 and derivatives
PRJNA604919 | ENA
UnknownRole of nuclear pools of aminoacyl-tRNA synthetases in tRNA nuclear export.
Not available
S-EPMC34591 | biostudies-literature
GenomicsYAMAT-seq of mature tRNA pools in the bacterium Pseudomonas fluorescens SBW25 and derivatives.
YAMAT-seq of mature tRNA pools in the bacterium Pseudomonas fluorescens SBW25 and derivatives.
PRJNA806938 | ENA
GenomicsYAMAT-seq of mature tRNA pools in the bacterium Escherichia coli str. K-12 substr. MG1655 and derivatives
YAMAT-seq of mature tRNA pools in the bacterium Escherichia coli str. K-12 substr. MG1655 and derivatives
PRJNA816107 | ENA
UnknownSelective gene expression maintains human tRNA anticodon pools during differentiation.
Not available
S-EPMC10791582 | biostudies-literature
GenomicsTransfer RNA pools in human cells are controlled by selective gene expression [tRNA-Seq]
Transfer RNAs are required for translating genetic information into protein sequence. The human genome contains hundreds of tRNA genes, many of which in multiple copies. How their expression is regulated to control functional tRNA levels is unknown. Here, we combined quantitative tRNA profiling and ...
ORGANISM(S): Homo sapiens 
2023-10-23 | GSE227927 | GEO
GenomicsYAMAT-seq of mature tRNA pools in the bacterium Escherichia coli str. K-12 substr. MG1655 and derivatives
Mature tRNA pools were measured using an adaptation of YAMAT-seq (Shigematsu et al., 2017; doi:10.1093/nar/gkx005 ) and further described in (Ayan et al., 2020; doi:10.7554/eLife.57947) in 10 strain-medium combinations (all strains dervied from the model bacterium E. coli MG1655). The aim of the exp...
ORGANISM(S): Escherichia coli K-12 
2022-12-02 | GSE198606 | GEO
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