Sort   by:  
 Page size 
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS674 | MetaboLights
MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
ProteomicsTau interactome mapping reveals dynamic processes associated with neurodegenerative diseases
The Tau (MAPT) protein drives neuronal dysfunction and toxicity in the brain in Alzheimer’s disease (AD) and other Tauopathies. To dissect the complexity of the Tau interactome that underlies this process we used two proteomic approaches to characterize the dynamic and multifaceted nature of Tau pro...
ORGANISM(S): Homo sapiens (Human) 
2022-01-11 | PXD026306 | Pride
Apex Ppi Tau 
UnknownPharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.
Not available
S-EPMC3462009 | biostudies-literature
UnknownCerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.
Not available
S-EPMC5916324 | biostudies-literature
UnknownGenome-wide association study and functional validation implicates JADE1 in tauopathy.
Not available
S-EPMC8786260 | biostudies-literature
UnknownBrain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
Not available
S-EPMC3369937 | biostudies-literature
UnknownEarly Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy.
Not available
S-EPMC8453611 | biostudies-literature
UnknownMultisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG).
Not available
S-EPMC6251511 | biostudies-literature
UnknownInterpretable deep learning of myelin histopathology in age-related cognitive impairment.
Not available
S-EPMC9490907 | biostudies-literature
Sort   by:  
 Page size