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TranscriptomicsGene expression and synergistic interactions induced by CpG ODN and/or poly(I:C)
Bioinformatic analysis of microarray data was used to identify the regulatory patterns underlying changes in gene expression induced when RAW 264.7 macrophages were stimulated via TLR9 by CpG oligonucleotides (ODN) and/or via TLR3 by poly (I:C). While the genes activated by each ligand mediated simi...
ORGANISM(S): Mus musculus 
2009-07-21 | E-GEOD-15416 | biostudies-arrayexpress
TranscriptomicsEffect of TLR Ligation on the Differentiation and Function of Human mMDSC
Immunosuppressive microenvironments block the activity of tumoricidal T and NK cells, allowing cancers to avoid immune elimination. Monocytic myeloid-derived suppressor cells (mMDSC) are an important component of these immunosuppressive milieus. Human mMDSC respond to stimulation via their Toll-li...
ORGANISM(S): Homo sapiens 
2014-07-21 | E-GEOD-57032 | biostudies-arrayexpress
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