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This article provides the first proteomic analysis of platelets from COVID-19 patients. Our dataset shows that platelets are reprogrammed during severe COVID-19 and respond with the activation of type I interferon and cell death pathways, indicating platelet participation in the antiviral response. ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD031251 | Pride
In this project we performed a comprehensive exploration of monocyte molecular responses in a cohort of patients with septic shock via label-free shotgun proteomics. We enrolled adult (≥18 years old) patients with sepsis from community-acquired infections, diagnosed according to the Third Internatio...
ORGANISM(S): Homo sapiens (Human) 
2021-09-07 | PXD023938 | Pride
Background: Extracellular vesicles are a valuable source of biomarkers and display the pathophysiological status of various diseases. In COVID-19, EVs are explored in several studies for their ability to reflect molecular changes caused by SARS-CoV-2 infection and impacts on disease progression. Met...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD032808 | Pride
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