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TranscriptomicsElk1 Directs a Critical Component of Growth Signaling by the Androgen Receptor in Prostate Cancer
Elk1 directs selective gene induction that is a substantial and critical component of growth signaling by AR in PC cells. Gene expression in LNCaP cells was determined in androgen-depleted medium in response to R1881 in ELK1 knock down (via AR shRNA) or in cells treated with control shRNA.
ORGANISM(S): Homo sapiens 
2013-05-02 | E-GEOD-34589 | biostudies-arrayexpress
TranscriptomicsHormone-Independence of Prostate Cancer Cells is Supported by the Androgen Receptor without Binding to Classical Response Elements
Treatment of late passage (LP50) LNCaP cells with R1881 (androgen) and AR shRNA identified a gene program controlled by androgen receptor in the absence of androgen. Gene expression in late passage (LP50) LNCaP cells that had enhanced androgen-independent growth was determined in androgen-depleted m...
ORGANISM(S): Homo sapiens 
2011-01-28 | E-GEOD-22483 | biostudies-arrayexpress
TranscriptomicsUnder conditions of hormonal adjuvant treatment the estrogen receptor apoprotein supports breast cancer cell cycling through the retinoic acid receptor M-NM-11 apoprotein
Under conditions of hormonal adjuvant treatment the estrogen receptor apoprotein supports breast cancer cell cycling through the retinoic acid receptor M-NM-11 apoprotein. Basal proliferation persisted in estrogen-sensitive breast cancer cells grown in hormone depleted conditioned media without or w...
ORGANISM(S): Homo sapiens 
2011-05-13 | E-GEOD-26298 | biostudies-arrayexpress
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