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MetabolomicsDivergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition
Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma congolense. In comparison to the well-studied T. brucei, there is a major paucity of knowledge regarding the biology of T. congole...
2021-07-20 | MTBLS2372 | MetaboLights
MetabolomicsVeterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights
TranscriptomicsTranscription profiling time series of lymph node, liver and spleen from two cattle breeds infected with Trypanosoma congolense to investigate breed differences in susceptibility
In this experiment, cattle from 2 breeds Boran and N'Dama were infected with Trypanosoma Congolense, IL1180 clone, African sleeping sickness, a disease which affects cattle in sub-saharan Africa. These breeds were chosen because they differ in their tolerance to infection, with Boran being highly su...
ORGANISM(S): Bos taurus 
2009-06-30 | E-MEXP-1778 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver and spleen RNA samples compared between A/J and C57BL/6 mice and between C57BL/6 wild type and TNF knockouts at five time points following Trypanosoma Congolense infection
Liver and Spleen RNA samples were compared between A/J and C57BL/6 mice and between C57BL/6 wildtype and TNF knockouts at five time points following Trypanosoma Congolense infection
ORGANISM(S): Mus musculus 
2013-01-30 | E-TIGR-109 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver and spleen RNA samples compared between A/J and C57BL/6 mice and between C57BL/6 wild type and TNF knockouts at five time points following Trypanosoma Congolense infection
Liver and Spleen RNA samples were compared between A/J and C57BL/6 mice and between C57BL/6 wildtype and TNF knockouts at five time points following Trypanosoma Congolense infection
ORGANISM(S): Mus musculus 
2013-01-30 | E-TIGR-108 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of PBMC from two cattle breeds infected with Trypanosoma congolense
Affymetrix® Bovine Genome Array data sets generated for 40 peripheral blood mononuclear cell (PBMC) samples from 10 African cattle (5 trypanotolerant N’Dama and 5 trypanosusceptible Boran) collected at four time points (before infection and at 14, 25, and 34 days post infection) for a Trypanosoma co...
ORGANISM(S): Bos taurus 
2025-07-17 | E-MTAB-14517 | biostudies-arrayexpress
GenomicsTrypanosoma congolense strain:1/148
Trypanosoma congolense metacyclic RNAseq
PRJNA399822 | ENA
GenomicsTrypanosoma congolense strain:IL3000
Trypanosoma congolense strain:IL3000 Genome sequencing
PRJNA1431949 | ENA
TranscriptomicsTrypanosoma congolense transcriptome sequencng
Transcriptome sequencng of Trypanosoma congolense for future protein-protein interaction studiesThis data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), pl...
ORGANISM(S): Trypanosma congolense 
2016-02-17 | E-ERAD-440 | biostudies-arrayexpress
GenomicsTrypanosoma congolense IL3000
Trypanosoma congolense IL3000 Genome sequencing and assembly
PRJNA432511 | ENA
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