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MetabolomicsMicrobial tryptophan metabolism orchestrated by trilobatin through TPH1 activation protects against acute kidney injury
Background: Acute kidney injury (AKI) remains a major clinical challenge with limited therapeutic options. Gut microbiota dysbiosis plays a crucial role in the pathogenesis of AKI. Trilobatin (TLB), has been previously reported to modulate gut microbiota and exert neuroprotective effects; however, i...
2026-04-05 | MTBLS14222 | MetaboLights
GenomicsSequencing_emtph
Sequencing of the Echinococcus multilocularis tryptophan hydroxylase gene
PRJEB22754 | ENA
UnknownThe regulatory domain of human tryptophan hydroxylase 1 forms a stable dimer.
Not available
S-EPMC4935573 | biostudies-literature
UnknownMechanisms of tryptophan and tyrosine hydroxylase.
Not available
S-EPMC4270200 | biostudies-literature
UnknownFunctional polymorphisms of the brain serotonin synthesizing enzyme tryptophan hydroxylase-2.
Not available
S-EPMC2792355 | biostudies-literature
UnknownMechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis.
Not available
S-EPMC2885594 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis sav mutants
Plants grown at high densities perceive a decrease in the red to far-red (R:FR) ratio of incoming light, resulting from absorption of red light by canopy leaves and reflection of far-red light from neighboring plants. These changes in light quality trigger a series of responses known collectively as...
ORGANISM(S): Arabidopsis thaliana 
2008-06-16 | E-GEOD-9816 | biostudies-arrayexpress
UnknownMolecular docking of bacosides with tryptophan hydroxylase: a model to understand the bacosides mechanism.
Not available
S-EPMC4111882 | biostudies-literature
UnknownCryo-EM Structure and Activator Screening of Human Tryptophan Hydroxylase 2.
Not available
S-EPMC9420949 | biostudies-literature
UnknownIdentification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases.
Not available
S-EPMC5418348 | biostudies-literature
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