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GenomicsComparative analysis of TAL1 binding in TSA-treated versus non-treated Endothelial Colony Forming Cells (ECFCs)
Endothelial progenitors represent one of the most promising cell-based strategies for vascular repair of ischemic tissue damage, including limb ischemia, myocardial infarction and stroke. We have shown that the transcription factor TAL1 regulates a transcription program that drives the migration and...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-53423 | biostudies-arrayexpress
GenomicsCitrobacter sp. TSA-1
Citrobacter sp. TSA-1 Genome sequencing and assembly
PRJNA396906 | ENA
TranscriptomicsTranscription profiling of Arabidopsis seed germination in presence and absence of histone deaceatylase inhibitor, Trichostain A (TSA).
Histone acetylation is involved in the regulation of gene expression in plants and eukaryotes. Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl groups from histones, which is associated with the repression of gene expression. To study the role of histone acetylation in ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-12 | E-GEOD-3784 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis treated with Trichostatin A (TSA) to inhibit of histone deacetylase in Arabiodopsis thaliana
Histone acetylation is involved in the regulation of gene expression in plants and eukaryotes. Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl groups from histones, which is associated with the repression of gene expression. To study the role of histone acetylation in ...
ORGANISM(S): Arabidopsis thaliana 
2008-06-12 | E-GEOD-3783 | biostudies-arrayexpress
GenomicsCitrobacter sp. TSA-1
Citrobacter sp. TSA-1 Genome sequencing
PRJNA623957 | ENA
TranscriptomicsMicroarray analysis of human monocytic THP-1 cell treated with 1α,25-dihydroxyvitamin D3 or Trichostatin A and the combination of both
The nuclear hormone 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) regulates its target genes via activation of the transcription factor vitamin D receptor (VDR) far more specifically than the chromatin modifier trichostatin A (TsA) via its inhibitory action on histone deacetylases. We selected the thro...
ORGANISM(S): Homo sapiens 
2012-10-25 | E-GEOD-36323 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
This experiment is part of the FunGenES project (FunGenES - Functional Genomics in Embryonic Stem Cells partially funded by the 6th Framework Programme of the European Union, http://www.fungenes.org). The experiment was conducted at the Institute for Molecular Biology and Biotechnology FORTH, Herakl...
ORGANISM(S): Mus musculus 
2009-07-10 | E-TABM-670 | biostudies-arrayexpress
TranscriptomicsExpression analysis of trichostatin A-treated Aspergillus fumigatus Af293
Investigation of whole genome gene expression level changes in trichostatin A (TSA)-treated A. fumigatus Af293 compared to non-treated A. fumigatus Af293. Species: Aspergillus fumigatus; Strain: Af293; Type of array: Eukaryotic Expression (4plex, 2plex for a TSA-treated sample and 2plex for a non-tr...
ORGANISM(S): Aspergillus fumigatus Af293 
2010-06-30 | E-GEOD-19682 | biostudies-arrayexpress
GenomicsBacillus sp. TSA-4
Bacillus sp. TSA-4 Genome sequencing
PRJNA1023046 | ENA
TranscriptomicsTranscription profiling of murine neurosphere cultures carrying a Bcl2 transgene and treated with histone deacetylase inhibitor Trichostatin A and demethylating agent AzaC to study DNA methylation and histone deacetylation in neural stem cells.
Neurosphere cultures were established from individually isolated E 14.5 forebrains of mouse embryos that carry a bcl2 transgene. Single-cell suspensions were prepared, seeded at 1x105 cells/ml and treated for two days with 150 nM Trichostatin A (TSA; histone deacetylase inhibitor), 500 nM 5-Aza-2-de...
ORGANISM(S): Mus musculus 
2007-12-19 | E-GEOD-587 | biostudies-arrayexpress
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