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The contribution of DNA methylation on the evolution of chronic lymphocytic leukemia has not been adequately studied yet. The purpose of this study was to investigate the role of DNA methylation in patients under chemoimmunotherapy. The overtime analysis of DNA methylation was performed on 40 patien...
ORGANISM(S): Homo sapiens 
A protein aggregation model of human ataxin-1(Q82) was generated in human mesenchymal cells using the Sleeping Beauty transposon system. These cells inducibly express the pathogenic protein that causes SCA1 disease. Here, we describe the transcriptional changes occurring in cells which contain diffe...
ORGANISM(S): Homo sapiens 
Identification of TP63 binding profile (cistrome) at a genome-wide scale in MEC1 cell line, an established and well-characterized cellular model of Chronic Lymphocytic Leukemia.
ORGANISM(S): Homo sapiens 
Identification of TP63 binding profile (cistrome) at a genome-wide scale, in primary cells derived from patient diagnosed with Chronic Lymphocytic Leukemia.
ORGANISM(S): Homo sapiens 
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