Tsoi K L KL - OmicsDI

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Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in ovary and testis

Stable activation of the WNT signaling effector beta-catenin (CTNNB1(ex3) in ovarian granulosa cells results in the formation of premalignant lesions that develop into granulosa cell tumors (GCTs) spontaneously later in life. Loss of the tumor suppressor gene Pten accelerates GCT formation in the CT...

ORGANISM(S): Mus musculus

2011-09-19 | E-GEOD-27656 | biostudies-arrayexpress

Development of a porcine (Sus scofa) embryo-specific microarray: array annotation and validation

Background The domestic pig is an important livestock species for meat production worldwide and is becoming an established biomedical research model. As a result, there is a strong interest in the factors that affect the efficient production of viable embryos and offspring in this species using eit...

ORGANISM(S): Sus scrofa

2013-02-25 | E-GEOD-35042 | biostudies-arrayexpress

The polygenic architecture of hidradenitis suppurativa reveals signaling mechanisms that implicate epithelial remodeling.

Not available

S-EPMC12324615 | biostudies-literature

Association between body weight and tocilizumab effectiveness in rheumatoid arthritis: results from the BSRBR-RA.

Not available

S-EPMC11781575 | biostudies-literature

Extended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.

Not available

S-EPMC11894929 | biostudies-literature

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.