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TranscriptomicsTranscription profiling of mouse CD4+ T cells gene-transduced with AML1, wild type Foxp3, and a Foxp3 mutant defective in binding to AML1
To clarify how Foxp3 regulates its target genes, we performed co-immunoprecipitation experiments and found that Foxp3 physically bound to AML1/Runx1 (Ono, M. et al, Nature, 2007). In this series of study, we compared gene regulations by AML1, wild type Foxp3, and a Foxp3 mutant with defective bindin...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-6939 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human NOR1- and EWS/NOR1-overexpressing 293 cells
To examine the differences between NOR1 and its fusion gene product EWS/NOR1, we compared the gene expression profiles of NOR1- and EWS/NOR1-overexpressing 293 cells. Experiment Overall Design: We established 293-tet-On clones stably transfected NOR1- or EWS/NOR1-expressing plasmid. Total RNA was co...
ORGANISM(S): Homo sapiens 
2009-01-14 | E-GEOD-11185 | biostudies-arrayexpress
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