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TranscriptomicsIL-4 mediated gene expression profiles in vascular endothelial cells
Endothelial cell activation and dysfunction underlie many vascular disorders, including atherosclerosis and inflammation. Here, we show that interleukin (IL)-4 markedly induced vascular cell adhesion molecule (VCAM)-1, both in cultured endothelial cells and in the intact endothelium in mice. Combine...
ORGANISM(S): Homo sapiens 
2011-05-01 | E-GEOD-28117 | biostudies-arrayexpress
GenomicsGenome-wide maps of MEF2C and H3K27ac localization in HUVECs
MEF2C is one of the substantially expressed transcriptional factors in endothelial cells, but its genomic localization is unknown. This time, we established a new antibody for MEF2C, and performed ChIP-seq to identify MEF2C binding site in whole genome manner. H3K27Ac binding sites were also detec...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-32644 | biostudies-arrayexpress
TranscriptomicsGATA2 in human vascular endothelial cells
GATA2 is well recognized as a key transcription factor and regulator of cell type specificity and differentiation. Here, we carried out comparative chromatin immunoprecipitation with comprehensive sequencing (ChIP-seq) to determine genome-wide occupancy of GATA2 in endothelial cells and erythroids, ...
ORGANISM(S): Homo sapiens 
2011-06-13 | E-GEOD-28304 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of the egg and synergid cell in rice
To reveal comprehensive gene expression profiles and their characteristics of the rice egg and synergid cell, we performed cell type-specific microarray analysis using nonenzymatic cell isolation technique. 40 and 50 genes expressed specifically in the egg cell and synergid cell were identified by c...
ORGANISM(S): Oryza sativa 
2010-12-01 | E-GEOD-21074 | biostudies-arrayexpress
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