Tu Zheng J ZJ - OmicsDI

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Unknown (9)
Metabolomics (6)

Repository

MetaboLights (6)

Technology Type

Mass spectrometry (6)

Instrument Platform

Liquid Chromatography MS - positive - reverse phase (3)
Liquid Chromatography MS - negative - reverse phase (2)
Liquid Chromatography MS - positive - hilic (2)
Liquid Chromatography MS - negative - hilic (1)
TripleTOF 6600, AB Sciex (1)

Publication Date

2021 (3)
2020 (2)
2018 (1)

CHEBI ID

CHEBI:15577 (3)
CHEBI:15891 (3)
CHEBI:17368 (3)
CHEBI:34980 (3)
CHEBI:41633 (3)
CHEBI:75036 (3)
CHEBI:10 (2)
CHEBI:100241 (2)
CHEBI:10043 (2)
CHEBI:10110 (2)
CHEBI:1019 (2)
CHEBI:102216 (2)
CHEBI:102265 (2)
CHEBI:10303 (2)
CHEBI:10447 (2)
CHEBI:10516 (2)
CHEBI:10578 (2)
CHEBI:1098 (2)
CHEBI:109895 (2)
CHEBI:11 (2)
CHEBI:11060 (2)
CHEBI:116314 (2)
CHEBI:116735 (2)
CHEBI:1296 (2)
CHEBI:15336 (2)
CHEBI:15367 (2)
CHEBI:15373 (2)
CHEBI:15417 (2)
CHEBI:15558 (2)
CHEBI:15559 (2)

Metabolite Name

(25R)-26-Hydroxycholest-4-en-3-one (2)
(25S)-26-Hydroxycholest-4-en-3-one (2)
(3R)-11-cis-3-Hydroxyretinal (2)
(3S)-11-cis-3-Hydroxyretinal (2)
(5Z,7E,9E,14Z,17Z)-Eicosapentaenoic acid (2)
(E,E,E)-N-(2-Methylpropyl)hexadeca-2,6,8-trien-10-ynamide (2)
(R)-6-Hydroxynicotine (2)
1(2H)-Phthalazinone (2)
1,1,2-Triphenylpropane (2)
1,2,3,4,4a,9,10,10a-Octahydro-6-hydroxy-7-isopropyl-1,4a-dimethyl-1-phenanthrenemethanol (2)
1,3,5,7,9,11,13-Pentadecaheptaene (2)
1,3-Dihydroxy-N-methylacridone (2)
1,3-Diphenylpropane (2)
1,4'-Bipiperidine-1'-carboxylic acid (2)
1,4-Dihydroxy-2-methylanthraquinone (2)
1,5-Naphthalenediamine (2)
1,8-Dimethylnaphthalene (2)
1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide (2)
1-Hydroxy-2-acetamidofluorene (2)
1-Methyladenosine (2)
1-Naphthylamine (2)
1-O-Hexadecyl-lyso-sn-glycero-3-phosphocholine (2)
11-cis-Retinal (2)
11alpha,17beta-Dihydroxy-17alpha-methylandrosta-1,4-dien-3-one (2)
11beta,17beta-Dihydroxy-17alpha-methylandrosta-1,4-dien-3-one (2)
13-cis-Retinal (2)
16beta-Hydroxy-3,11-dioxopregna-4,17(20)-dien-21-oic acid, gamma-lactone (2)
17,17-Dimethyl-18-norandrosta-4,13-dien-3-one (2)
17-Hydroxy-19-nor-17alpha-pregn-5(10)-en-3-one (2)
17-Methyl-18-norandrosta-4,13(17)-dien-3-one (2)

Release Date

2023 (2)
2022 (1)
2021 (1)
2020 (1)
2019 (1)
2018 (1)
2016 (1)
2013 (1)

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Absolute quantitative lipidomics reveals lipidome-wide alterations in aging brain (Mouse brain NEG UPLC-MS assay)

INTRODUCTION: The absolute quantitation of lipids at the lipidome-wide scale is a challenge but plays an important role in the comprehensive study of lipid metabolism.

OBJECTIVES: We aim to develop a high-throughput quantitative lipidomics approach to enab...

2018-08-03 | MTBLS495 | MetaboLights

Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly

Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...

2021-10-06 | MTBLS1503 | MetaboLights

Ion mobility-based sterolomics reveals spatially and temporally distinctive sterol lipids in the mouse brain

Aberrant sterol lipid metabolism is associated with physiological dysfunctions in the aging brain and aging-dependent disorders such as neurodegenerative diseases. There is an unmet demand to comprehensively profile sterol lipids spatially and temporally in different brain regions during aging. Here...

2021-05-24 | MTBLS2457 | MetaboLights

Unknown Metabolite Annotation in Mouse Aging using Ion Mobility Collision Cross-Section Atlas (AllCCS)

The metabolome includes not just known but also unknown metabolites; however, metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility – mass spectrometry (IM-MS) has emerged as a promising technology by providing multi-dimensional characterizations of metabolites. He...

2020-07-28 | MTBLS1622 | MetaboLights

Prediction and evaluation of the effect of pre-centrifugation sample management on the measurable untargeted LC-MS plasma metabolome

Optimal handling is the most important means to ensure adequate sample quality. We aimed to investigate whether pre-centrifugation delay time and temperature could be accurately predicted and to what extent variability induced by pre-centrifugation management can be adjusted for. We used untarget...

2021-10-13 | MTBLS2259 | MetaboLights

Known Metabolite Annotation in Different Biological Samples using Ion Mobility Collision Cross-Section Atlas (AllCCS)

2020-07-28 | MTBLS1693 | MetaboLights

Factors associated with door-in to door-out delays among ST-segment elevation myocardial infarction (STEMI) patients transferred for primary percutaneous coronary intervention: a population-based cohort study in Ontario, Canada.

Not available

S-EPMC6206901 | biostudies-literature

Barriers and enablers in the implementation of a quality improvement program for acute coronary syndromes in hospitals: a qualitative analysis using the consolidated framework for implementation research.

Not available

S-EPMC9158188 | biostudies-literature

Assessing risk factors for SARS-CoV-2 infection in patients presenting with symptoms in Shanghai, China: a multicentre, observational cohort study.

Not available

S-EPMC7255260 | biostudies-literature