Sort   by:  
 Page size 
MetabolomicsLarge neutral amino acid levels tune perinatal neuronal excitability and survival
Surprisingly little is known about the critical metabolic changes that neural cells have to undergo during development and how even mild, temporary shifts in this program can influence brain circuitries and behavior. Inspired by the discovery that mutations in SLC7A5, a transporter of metabolically-...
2023-03-28 | MTBLS6578 | MetaboLights
MetabolomicsEssential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the developing brain

Omega-3 fatty acids (n-3 polyunsaturated fatty acids; n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary intake of n-3 PUFAs. Low maternal intake of n...

2020-11-03 | MTBLS1952 | MetaboLights
GenomicsBase editing mutagenesis maps functional alleles to tune human T cell activity
Base editing mutagenesis maps functional alleles to tune human T cell activity
PRJNA1024532 | ENA
GenomicsKDM6 Histone Demethylases Tune Pancreatic Cancer Plasticity
KDM6 Histone Demethylases Tune Pancreatic Cancer Plasticity
PRJNA1504960 | ENA
Genomics5' Untranslated regions tune Toxoplasma translation [MPRA]
5' Untranslated regions tune Toxoplasma translation [MPRA]
PRJNA1288538 | ENA
GenomicsKDM6 Histone Demethylases Tune Pancreatic Cancer Plasticity
KDM6 Histone Demethylases Tune Pancreatic Cancer Plasticity
PRJNA835430 | ENA
GenomicsH3K4me3/H3K27me3 bivalent chromatin function to fine-tune gene expression level
H3K4me3/H3K27me3 bivalent chromatin function to fine-tune gene expression level
PRJNA428482 | ENA
Genomics5' Untranslated regions tune Toxoplasma translation [Ribosome Profiling]
5' Untranslated regions tune Toxoplasma translation [Ribosome Profiling]
PRJNA1288540 | ENA
GenomicsB-Box protein 28 and BBX29 Interplay with PSEUDO-RESPONSE REGULATORS to Fine-tune Circadian Clock in Arabidopsis
B-Box protein 28 and BBX29 Interplay with PSEUDO-RESPONSE REGULATORS to Fine-tune Circadian Clock in Arabidopsis
PRJNA855934 | ENA
OtherBase editing mutagenesis maps functional alleles to tune human T cell activity
CRISPR-enabled genetic screening is a powerful tool to discover genes that control T cell function and has nominated candidate target genes for immunotherapies1–6. However, new approaches are required to probe specific nucleotide sequences within key genes. Systematic mutagenesis in primary human T ...
ORGANISM(S): Homo sapiens 
2023-10-11 | GSE244774 | GEO
Sort   by:  
 Page size