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UnknownMachine Learning Analysis of Blood microRNA Data in Major Depression: A Case-Control Study for Biomarker Discovery.
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S-EPMC7689198 | biostudies-literature
TranscriptomicsConserved epigenetic sensitivity to early life experience in the rat and human hippocampus
Early life experience is associated with long-term effects on behavior and epigenetic programming of the NR3C1 (glucocorticoid receptor) gene in the hippocampus of both rats and humans. However, it is unlikely that such effects completely capture the evolutionarily conserved epigenetic mechanisms of...
ORGANISM(S): Homo sapiens 
2012-05-30 | E-GEOD-38352 | biostudies-arrayexpress
TranscriptomicsDifferential microRNA profile in frontal cortex of suicide completers compared to control
Background: TrkB-T1 is a BDNF receptor lacking a tyrosine kinase domain that is highly expressed in astrocytes and regulates BDNF-evoked calcium transients. Previous studies indicate that downregulation of TrkB-T1 in frontal cortex may be involved in neurobiological processes underlying suicide. Me...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-GEOD-34120 | biostudies-arrayexpress
TranscriptomicsDNA modification study in major depressive disorder
Major depressive disorder (MDD) exhibits numerous clinical, epidemiological, and molecular features that are consistent with partially inherited and partially acquired epigenetic misregulation. We performed microarray based DNA modification study of MDD, utilizing affected and unaffected samples fro...
ORGANISM(S): Homo sapiens 
2012-04-27 | E-GEOD-37579 | biostudies-arrayexpress
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