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TranscriptomicsLongSAGE transcriptome profiling in the widespread marine coccolithophore Emiliania huxleyi
The abundant and widespread coccolithophore Emiliania huxleyi plays an important role in mediating CO2 exchange between the ocean and the atmosphere through its impact on marine photosynthesis and calcification. Here, we use long serial analysis of gene expression (SAGE) to identify E. huxleyi genes...
ORGANISM(S): Emiliania huxleyi CCMP1516 
2007-07-07 | E-GEOD-8376 | biostudies-arrayexpress
TranscriptomicsGene expression changes associated with resistance to intravenous corticosteroid therapy in children with severe ulcerative colitis
Although corticosteroids remain a mainstay of therapy for UC, a meta-regression of cohort studies in acute severe ulcerative colitis (UC) showed that 29% of patients fail corticosteroid therapy and require escalation of medical management or colectomy. We aimed to determine whether genes expressed i...
ORGANISM(S): Homo sapiens 
2010-08-31 | E-GEOD-21231 | biostudies-arrayexpress
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
GenomicsNIDDK IBD Genetics Consortium Crohn's Disease Genome-Wide Association Study

This dataset contains data from a genome-wide association study performed with 968 Inflammatory Bowel Disease (IBD) affected cases and 995 unrelated controls using the Illumina HumanHap300 Genotyping BeadChip. Cases were selected to have Crohn's disease with ileal involvement, and con...

phs000130.v1.p1 | EGA
UnknownA connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection.
Not available
S-EPMC9477501 | biostudies-literature
UnknownFast Optimization of Robust Transcriptomics Embeddings using Probabilistic Inference Autoencoder Networks for multi-Omics.
Not available
S-EPMC12642614 | biostudies-literature
UnknownThe Missing Piece of the Puzzle: Unveiling the Role of <i>PTPN11</i> Gene in Multiple Osteochondromas in a Large Cohort Study.
Not available
S-EPMC11918999 | biostudies-literature
UnknownAlbendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis.
Not available
S-EPMC5692564 | biostudies-literature
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
TranscriptomicsTranscription profiling of murine GATA-1 wild type and mutant fetal megakaryocytes to understand the molecular basis for the megakaryocytic hyperproliferation phenotype of the GATA-1deltaN mutants
Background: Children with Down syndrome (DS) are predisposed to acute megakaryoblastic leukemia (AMKL, or AML M7) and a related myeloid disorder, referred to as transient myeloproliferative disorder (TMD), or transient leukemia (TL). Recently, acquired mutations in the erythroid/megakaryocytic linea...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2433 | biostudies-arrayexpress
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