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TranscriptomicsSphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis
Sphingosine 1-phosphate (S1P) is a bioactive lipid whose levels are tightly regulated by its synthesis and degradation. Intracellularly, S1P is dephosphoryled by the actions of two S1P-specific phosphatases, sphingosine 1-phosphate phosphatase 1 and 2. To identify the physiologic functions of S1P p...
ORGANISM(S): Mus musculus 
2013-08-09 | E-GEOD-40368 | biostudies-arrayexpress
TranscriptomicsSphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet B-cell Endoplasmic Reticulum Stress and Proliferation
Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that regulates basic cell functions through metabolic and signaling pathways. Intracellular metabolism of S1P is controlled, in part, by two homologous S1P phosphatases, 1 and 2, which are encoded by Sgpp1 and Sgpp2, respectively. S1P phosph...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-73131 | biostudies-arrayexpress
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