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UnknownBET inhibitor resistance emerges from leukaemia stem cells.
Not available
S-EPMC6069604 | biostudies-literature
GenomicsChIP of BET proteins in iBET resistance [ChIP-seq]
Bromodomain and Extra Terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a new therapeutic paradigm by directly targeting epigenetic readers1,2. Early clinical trials have shown significant promise especially in acute myeloid leukaemia (AML)3; therefore the evaluati...
ORGANISM(S): Mus musculus 
2015-09-15 | E-GEOD-63682 | biostudies-arrayexpress
TranscriptomicsGenome wide expression analysis of BET inhibitor resistance [RNA-seq]
Bromodomain and Extra Terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a new therapeutic paradigm by directly targeting epigenetic readers1,2. Early clinical trials have shown significant promise especially in acute myeloid leukaemia (AML)3; therefore the evaluati...
ORGANISM(S): Mus musculus 
2015-09-15 | E-GEOD-63681 | biostudies-arrayexpress
TranscriptomicsGenome wide expression analysis of BET inhibitor resistance
Bromodomain and Extra Terminal protein (BET) inhibitors are first-in-class targeted therapies that deliver a new therapeutic paradigm by directly targeting epigenetic readers. Early clinical trials have shown significant promise especially in acute myeloid leukaemia (AML)3; therefore the evaluation ...
ORGANISM(S): Mus musculus 
2015-09-15 | E-GEOD-63575 | biostudies-arrayexpress
GenomicsHELIC_MANOLIS_ExomeChip - samples
Samples from the Greek island of Crete, MANOLIS cohort
EGAD00010000518 | EGA
Genomicsuk10k_cohort_twins_rel_2011_12_01-sc-20120629 - samples
UK10K_COHORT_TWINS REL-2011-12-01
EGAD00001000194 | EGA
Genomicsuk10k_cohort_imputation_rel_2012_06_02-sc-20140306 - samples
UK10K_COHORT_IMPUTATION REL-2012-06-02: imputation reference panel (20140306); Merged UK10K+1000Genomes Phase 3 imputation reference panel added (20160420)
EGAD00001000776 | EGA
Genomicsuk10k_cohort_alspac_rel_2011_12_01-sc-20120629 - samples
For information about this sample set, please contact the sample custodian Nic Timpson: N.J.Timpson@bristol.ac.uk
EGAD00001000195 | EGA
Genomicsuk10k_cohort_alspac_rel_2012_06_02-sc-20131101 - samples
UK10K_COHORT_ALSPAC REL-2012-06-02: Low-coverage whole genome sequencing; variant calling, genotype calling and phasing
EGAD00001000740 | EGA
Genomicsuk10k_cohort_twinsuk_rel_2012_06_02-sc-20131101-phenotypes - samples
UK10K_COHORT_TWINSUK REL-2012-06-02: Phenotype data
EGAD00001000790 | EGA
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