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Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder caused by loss-of-function mutations in PKD1 or PKD2. Increased glycolysis is a prominent feature of the disease, but how it impacts on other metabolic pathways is unknown. Here, we present an analysis of mouse Pkd1 mutant ce...
2019-06-07 | MTBLS677 | MetaboLights
Dissection of cMyc+ GC-B cells [WT]
Hyperglycemia, a common transient metabolic disturbance, is strongly associated with postoperative complications, yet the underlying immunometabolic mechanisms remain poorly understood. To investigate the impact of high glucose on monocytes in Stanford type A acute aortic dissection (ATAAD), we perf...
ORGANISM(S): Homo sapiens 
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