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CRISPR-Cas mediated DNA-interference typically relies on sequence-specific binding and nucleolytic degradation of foreign genetic material. Type IV-A CRISPR-Cas systems diverge from this general mechanism, using a nuclease-independent interference pathway to suppress gene expression for gene regulat...
ORGANISM(S): Pseudomonas oleovorans 
2024-10-08 | PXD056399 | Pride
Deep sequencing data from PAM screen of Pa83 type IV-A CRISPR-Cas system
IV CRISPR-Cas system displays PAM-dependent interference to vectors without showing nuclease activity to the target
Functional characterization of a plasmid-encoded type IV-A3 CRISPR-Cas system
In this work the favorable PAM sequences for a type IV-A CRISPR-Cas system were determined
ORGANISM(S): Escherichia coli 
2022-08-19 | GSE211446 | GEO
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