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ProteomicsThe molecular basis of regulation of bacterial capsule assembly by Wzc
Bacterial extracellular polysaccharides (EPSs) play critical roles in virulence as well as representing valuable bioproducts. Many bacteria use a “Wzx-Wzy-dependent” mechanism to assemble EPSs, in a tightly controlled multi-protein process that couples glycan polymerisation at the inner membrane to ...
ORGANISM(S): Escherichia coli 
2021-07-06 | PXD025820 | Pride
Phosphoproteomics Tyrosine autokinase E. coli 
ProteomicsMolecular basis for the phosphorylation of bacterial tyrosine kinase Wzc
The regulation of polymerisation and translocation are of fundamental interest in biology. The Wzc class of integral membrane tyrosine autokinase proteins serve as the master regulators of the biosynthesis and export of some bacterial capsular and exopolysaccharides. These polysaccharides play essen...
ORGANISM(S): Escherichia coli 
2025-03-27 | PXD061798 | Pride
Phosphorylation 
UnknownThe Tyrosine-Autokinase UbK Is Required for Proper Cell Growth and Cell Morphology of Streptococcus pneumoniae.
Not available
S-EPMC6733980 | biostudies-literature
UnknownMolecular basis for the phosphorylation of bacterial tyrosine kinase Wzc.
Not available
S-EPMC11986026 | biostudies-literature
UnknownBY-kinases: Protein tyrosine kinases like no other.
Not available
S-EPMC9800525 | biostudies-literature
UnknownFunctional analysis of Burkholderia cepacia genes bceD and bceF, encoding a phosphotyrosine phosphatase and a tyrosine autokinase, respectively: role in exopolysaccharide biosynthesis and biofilm formation.
Not available
S-EPMC1796985 | biostudies-literature
UnknownCrystal structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, representatives of two families of tyrosine phosphatases that regulate capsule assembly.
Not available
S-EPMC2777267 | biostudies-literature
UnknownThe role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803.
Not available
S-EPMC6562117 | biostudies-literature
UnknownThe molecular basis of regulation of bacterial capsule assembly by Wzc.
Not available
S-EPMC8285477 | biostudies-literature
ProteomicsThe proteome of wzc point mutation
wzc is a key protein in capsule synthesis, maturation and transport. As a tyrosine autokinase, wzc phosphorylation controls the opening and closing of capsular polysaccharide transport channels by influencing its own polymerization state. Studying the protein expression after wzc point mutation will...
ORGANISM(S): Klebsiella Pneumoniae Jh1 
2025-01-06 | PXD059483 |
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